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Stockholders’ Equity (Tables)
6 Months Ended
Jun. 30, 2021
Equity [Abstract]  
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs

 

 

  

Three Months Ended

June 30,

  

Six Months Ended

June 30,

 
   2021   2020   2021   2020 
                 
Research and development  $69,483   $199,777   $136,369   $334,441 
General and administrative   77,264    265,281    157,944    452,530 
Allocated Share-based Compensation Expense  $146,747   $465,058   $294,313   $786,971 
Schedule of Key Assumption of Fair Value of Stock Options Granted

 

   2021   2020 
Expected term   5.70 years    5.81 years 
Risk-free interest rate   0.52%   1.33%
Expected dividend yield        
Expected volatility   95.52%   99.52%
Schedule of Stock Option Activity

A summary of stock option activity is as follows:

 

   Outstanding stock options 
   Number of shares   Weighted average exercise price 
Balance at December 31, 2020   3,564,458   $3.36 
Options granted   376,000    1.44 
Options exercised   (4,584)   1.46 
Options forfeited   -    - 
Options cancelled   (20,084)   6.45 
Balance at June 30, 2021   3,915,790    3.16 
           
Options exercisable at June 30, 2021   2,528,729    4.24 
Schedule of Share-based Compensation of Stock Options Outstanding and Exercisable

The following table summarizes information about stock options outstanding and exercisable at June 30, 2021:

 

Options outstanding  Options exercisable
Number outstanding  Weighted average remaining contractual life (Years)   Weighted average exercise price   Aggregate intrinsic value   Number exerciseable  Weighted average remaining contractual life (Years)   Weighted average exercise price   Aggregate intrinsic value 
                                  
3,915,790   6.39   $3.16   $636,639   2,528,729   4.84   $4.24   $311,190 
Schedule of Fair Value of Warrants

 

   June 30, 2021   December 31, 2020 
Expected life in years   3.38    3.88 
Risk-free interest rate   0.46%   0.27%
Dividend yield        
Volatility   72.62%   88.46%
Stock price  $1.40   $1.36 
Schedule of Reconciliation of Warrant Liability

 

   Warrant Liability 
Balance at December 31, 2020  $1,170,051 
Settlement of liability on warrant exercise   (18,365)
Change in fair value of common stock warrants   (26,257)
Balance at June 30, 2021  $1,125,429 
Schedule of Number of Warrants Outstanding and the Weighted Average Exercise Price

The following table summarizes the number of common stock warrants outstanding and the weighted average exercise price:

   Warrants  

Weighted Average

Exercise Price

 
Outstanding at December 31, 2020   1,944,366   $0.51 
Issued   -    - 
Exercised   (10,000)   0.50 
Expired   -    - 
Cancelled   -    - 
Forfeited   -    - 
Balance at June 30, 2021   1,934,366   $0.51 
The following table summarizes information about common stock warrants outstanding at June 30, 2021:

 

Warrants outstanding
Number exercisable  Weighted average remaining contractual life (Years)   Weighted average exercise price   Aggregate intrinsic value 
                
1,934,366   3.50   $0.51   $1,715,719