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Contractual Agreements (Details Narrative) - USD ($)	3 Months Ended		6 Months Ended
	Jun. 30, 2021	Jun. 30, 2020	Jun. 30, 2021	Jun. 30, 2020
Entity Listings [Line Items]
Contract research and development expenses	$ 786,000	$ 1,200,000	$ 1,700,000	$ 2,900,000
Abbott Products Inc [Member] | Collaborative Arrangement [Member]
Entity Listings [Line Items]
Percentage of net sales			1.00%
Royalties, commitment amount	$ 1,000,000.0		$ 1,000,000.0
Percentage of royalties reduction based upon product launch			50.00%

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Percentage of royalties reduction based upon product launch.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 730
-SubTopic 10
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373

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The amount the entity has committed to make for future royalty guarantees.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 928
-SubTopic 440
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=6473578&loc=d3e63223-108013

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