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Cover - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2021
Mar. 07, 2022
Jun. 30, 2021
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Annual Report true    
Document Transition Report false    
Document Period End Date Dec. 31, 2021    
Document Fiscal Period Focus FY    
Document Fiscal Year Focus 2021    
Current Fiscal Year End Date --12-31    
Entity File Number 001-36357    
Entity Registrant Name LIPOCINE INC.    
Entity Central Index Key 0001535955    
Entity Tax Identification Number 99-0370688    
Entity Incorporation, State or Country Code DE    
Entity Address, Address Line One 675 Arapeen Drive    
Entity Address, Address Line Two Suite 202    
Entity Address, City or Town Salt Lake City    
Entity Address, State or Province UT    
Entity Address, Postal Zip Code 84108    
City Area Code 801    
Local Phone Number 994-7383    
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Trading Symbol LPCN    
Security Exchange Name NASDAQ    
Entity Well-known Seasoned Issuer No    
Entity Voluntary Filers No    
Entity Current Reporting Status Yes    
Entity Interactive Data Current Yes    
Entity Filer Category Non-accelerated Filer    
Entity Small Business true    
Entity Emerging Growth Company false    
Entity Shell Company false    
Entity Public Float     $ 120.5
Entity Common Stock, Shares Outstanding   88,290,650  
Documents Incorporated By Reference Portions of the registrant’s definitive Proxy Statement for its 2021 Annual Meeting of Stockholders are incorporated by reference into Part III of this Form 10-K    
ICFR Auditor Attestation Flag false    
Auditor Firm ID 270    
Auditor Name Tanner LLC    
Auditor Location Salt Lake City, Utah