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Contractual Agreements (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Jan. 01, 2026
Jan. 01, 2025
Oct. 14, 2021
Mar. 29, 2012
Dec. 31, 2020
Dec. 31, 2021
Dec. 31, 2020
Malpractice Insurance [Line Items]              
Revenue from Contract with Customer, Excluding Assessed Tax         $ 0    
Contract research and development expenses           $ 4,900,000 $ 6,800,000
Collaborative Arrangement [Member] | Abbott Products Inc [Member]              
Malpractice Insurance [Line Items]              
Percentage of net sales       1.00%      
Royalties, commitment amount       $ 1,000,000.0      
Percentage of royalties reduction based upon product launch       50.00%      
License Agreement [Member]              
Malpractice Insurance [Line Items]              
License fee     $ 11,000,000.0        
Percentage of royalty payment     20.00%        
Revenue from Contract with Customer, Excluding Assessed Tax           $ 16,100,000 $ 0
License Agreement [Member] | Maximum [Member]              
Malpractice Insurance [Line Items]              
Sales milestone     $ 160,000,000.0        
License Agreement [Member] | Subsequent Event [Member] | Forecast [Member]              
Malpractice Insurance [Line Items]              
Potential license fees from a licensee $ 5,000,000.0 $ 5,000,000.0          
License Agreement [Member] | TLANDO XR [Member]              
Malpractice Insurance [Line Items]              
License fee     4,000,000.0        
Clinical and development milestones     $ 35,000,000.0