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Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2020 | Dec. 31, 2019
--- | --- | ---
Deferred Tax Assets |  |
Accrued expenses | $ 455 | $ 277
License fees | 1,168 | 1,332
Stock Options | 3,759 | 2,584
Other | 228 | 115
State net operating loss carryforwards | 8,959 | 7,431
Federal net operating loss carryforwards | 33,711 | 47,845
Total deferred tax assets | 53,848 | 63,864
Valuation allowance | (53,669) | (63,737)
Net deferred tax asset (liability) | 179 | 127
Federal |  |
Deferred Tax Assets |  |
Research tax credits | 4,943 | 3,770
State |  |
Deferred Tax Assets |  |
Research tax credits | $ 625 | $ 510

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