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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2021
Income Taxes |
Schedule of income (loss) before income taxes | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ |  | 2021 |  | 2020
U.S. | ​ | $ | (39,155) | ​ | $ | (28,699)
Foreign | ​ |  | (1,456) | ​ |  | 1,183
Loss before income taxes | ​ | $ | (40,611) | ​ | $ | (27,516)
Schedule of Company's current and deferred expense for income tax | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ |  | 2021 |  | 2020
Current expense (benefit): | ​ | ​ | ​ | ​ | ​ | ​
Federal | ​ | $ | — | ​ | $ | —
State | ​ |  | — | ​ |  | —
Foreign | ​ |  | (37) | ​ |  | 40
Total current expense (benefit): | ​ | $ | (37) | ​ | $ | 40
Deferred expense (benefit): | ​ | ​ | ​ | ​ | ​ | ​
Federal | ​ | $ | — | ​ | $ | —
State | ​ |  | — | ​ |  | —
Foreign | ​ |  | 13 | ​ | ​ | (42)
Total deferred expense (benefit): | ​ | $ | 13 | ​ | $ | (42)
Total income tax expense (benefit): | ​ | $ | (24) | ​ | $ | (2)
​
Schedule of reconciliation of the Company's statutory income tax rate to the Company's effective income tax rate | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended |
​ | ​ | December 31, | ​
​ |  | 2021 |  | 2020 |
Income at US Statutory Rate |  | 21.0 | % | 21.0 | %
State Taxes, net of Federal benefit |  | 7.2 | % | 7.0 | %
Permanent Differences |  | (1.8) | % | (1.1) | %
Tax Credits |  | 3.9 | % | 6.0 | %
Foreign Rate Differential |  | 0.2 | % | (0.5) | %
Israel DTA write-off | ​ | 0.0 | % | (70.2) | %
Valuation Allowance |  | (30.6) | % | 36.6 | %
Other |  | 0.1 | % | 1.2 | %
​ |  | 0.0 | % | 0.0 | %
Schedule of significant components of the Company's deferred tax assets | ​
​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Year Ended
​ | ​ | December 31,
​ |  | 2021 |  | 2020
Accrued expenses | ​ | $ | 729 | ​ | $ | 455
License Fees | ​ | ​ | 1,004 | ​ |  | 1,168
Stock Options | ​ | ​ | 4,671 | ​ |  | 3,759
Other | ​ | ​ | 212 | ​ |  | 228
State net operating loss carryforwards | ​ | ​ | 11,246 | ​ |  | 8,959
State research tax credits | ​ | ​ | 1,006 | ​ |  | 625
Federal net operating loss carryforwards | ​ | ​ | 41,207 | ​ |  | 33,711
Federal research tax credits | ​ | ​ | 6,166 | ​ |  | 4,943
Total deferred tax assets | ​ | ​ | 66,241 | ​ | ​ | 53,848
Valuation allowance | ​ |  | (66,082) | ​ |  | (53,669)
Net deferred tax asset (liability) | ​ | $ | 159 | ​ | $ | 179
​

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- Definition Tabular disclosure of the components of income tax expense attributable to continuing operations for each year presented including, but not limited to: current tax expense (benefit), deferred tax expense (benefit), investment tax credits, government grants, the benefits of operating loss carryforwards, tax expense that results from allocating certain tax benefits either directly to contributed capital or to reduce goodwill or other noncurrent intangible assets of an acquired entity, adjustments of a deferred tax liability or asset for enacted changes in tax laws or rates or a change in the tax status of the entity, and adjustments of the beginning-of-the-year balances of a valuation allowance because of a change in circumstances that causes a change in judgment about the realizability of the related deferred tax asset in future years. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 9 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32639-109319 + Details
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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI http://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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