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Warrants (Details) $ / shares in Units, $ in Thousands |  |  |  |  | 12 Months Ended |
--- | --- | --- | --- | --- | --- | ---
Sep. 24, 2021 $ / shares shares | Jun. 22, 2020 $ / shares shares | Mar. 05, 2020 $ / shares shares | Jan. 03, 2020 Vote item $ / shares shares | Dec. 31, 2021 USD ($) $ / shares shares | Dec. 31, 2020 USD ($) $ / shares shares | Feb. 05, 2019 $ / shares shares
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 60,386,157 |  |
Warrant, Down Round Feature, (Increase) Decrease in Equity, Amount | $ |  |  |  |  |  | $ 303 |
January 23 2017 Warrants |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 54,516 |  |
Exercise price of warrant | $ / shares |  |  |  |  | $ 0.01 |  |
2017 Warrants |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 2,502,382 |  |
Exercise price of warrant | $ / shares |  |  |  |  | $ 1.055 | $ 1.75 |
Warrant, Down Round Feature, (Increase) Decrease in Equity, Amount | $ |  |  |  |  |  | $ 303 |
Gross proceeds | $ |  |  |  |  | $ 50 | $ 220 |
Number of warrants or rights exercised |  |  |  |  | 47,458 | 208,254 |
2019 Warrants |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 7,008,257 |  |
Exercise price of warrant | $ / shares |  |  |  |  | $ 1.95 |  | $ 1.95
Gross proceeds | $ |  |  |  |  | $ 943 | $ 128 |
Number of warrants or rights exercised |  |  |  |  | 483,185 | 65,700 |
Warrant to purchase shares of common stock |  |  |  |  |  |  | 7,557,142
March 2020 |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 14,413,902 |  |
Exercise price of warrant | $ / shares |  |  |  |  | $ 0.001 |  |
March 2020. |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 25,945,035 |  |
Exercise price of warrant | $ / shares |  |  |  |  | $ 2.11 |  |
June 2020 |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 1,690,137 |  |
Exercise price of warrant | $ / shares |  | $ 0.001 |  |  | $ 0.001 |  |
Number of warrants or rights exercised |  |  |  |  | 559,863 |  |
Warrant to purchase shares of common stock |  | 2,250,000 |  |  |  |  |
June 2020 | Common Stock. |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 559,705 |  |
June 2020 | Common Stock. |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Common stock issued |  | 20,250,000 |  |  |  |  |
Purchase price | $ / shares |  | $ 2.00 |  |  |  |  |
September 2021 |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Number of Shares Issuable |  |  |  |  | 8,771,928 |  |
Exercise price of warrant | $ / shares | $ 0.001 |  |  |  | $ 0.001 |  |
Common stock issued | 8,771,928 |  |  |  |  |  |
Purchase price | $ / shares | $ 2.85 |  |  |  |  |  |
Warrant to purchase shares of common stock | 8,771,928 |  |  |  |  |  |
September 2021 | Common Stock. |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Common stock issued | 22,828,072 |  |  |  |  |  |
Purchase price | $ / shares | $ 2.85 |  |  |  |  |  |
September 2021 | Common Stock. |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Common stock issued | 27,568,072 |  |  |  |  |  |
Purchase price | $ / shares | $ 0.001 |  |  |  |  |  |
March 2020 Warrants | Series A Convertible Preferred Stock |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Exercise price of warrant | $ / shares |  |  | $ 0.001 |  |  |  |
Common stock issued |  |  |  | 1,421,801 |  |  |
Purchase price | $ / shares |  |  |  | $ 10.54 |  |  |
Warrant to purchase shares of common stock |  |  | 14,413,902 |  |  |  |
Number of special voting stock | Vote |  |  |  | 1 |  |  |
Number of members to elect of board of directors | item |  |  |  | 1 |  |  |
March 2020 Warrants | Series B Convertible Preferred Stock |  |  |  |  |  |  |
Warrants |  |  |  |  |  |  |
Exercise price of warrant | $ / shares |  |  | $ 2.11 |  |  |  |
Common stock issued |  |  |  | 1,137,442 |  |  |
Purchase price | $ / shares |  |  |  | $ 10.55 |  |  |
Conversion of Stock, Shares Issued |  |  | 11,531,133 |  |  |  |

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