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Common stock - Public Offering of Common Stock (Details) - USD ($) $ / shares in Units, $ in Thousands	Sep. 24, 2021	Jun. 22, 2020	Dec. 31, 2021	Dec. 31, 2020	Feb. 05, 2019
Common stock, par value (in dollars per share)			$ 0.001	$ 0.001
2019 Warrants
Warrant to purchase shares of common stock					7,557,142
Exercise price of warrant			1.95		$ 1.95
June 2020
Warrant to purchase shares of common stock		2,250,000
Exercise price of warrant		$ 0.001	0.001
September 2021
Common stock issued	8,771,928
Issue price	$ 2.85
Warrant to purchase shares of common stock	8,771,928
Exercise price of warrant	$ 0.001		$ 0.001
Common Stock. | September 2021
Common stock issued	22,828,072
Issue price	$ 2.85
Net proceeds from issuance of common stock	$ 96,828
Underwriters' exercise | Common Stock. | September 2021
Common stock issued	4,740,000
Common Stock. | June 2020
Common stock issued		20,250,000
Issue price		$ 2.00
Net proceeds from issuance of common stock		$ 48,276
Common Stock. | September 2021
Common stock issued	27,568,072
Issue price	$ 0.001
Common Stock. | Underwriters' exercise | June 2020
Common stock issued		3,375,000

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