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CONSOLIDATED STATEMENT OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Series A Convertible Preferred Stock
Preferred Stock
Series A Convertible Preferred Stock
Series B Convertible Preferred Stock
Preferred Stock
Series B Convertible Preferred Stock
Common Stock.
Additional Paid-in Capital.
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Balance at the beginning of the period (in shares) at Dec. 31, 2019         24,194,877        
Increase (Decrease) in Shares Outstanding                  
Issuance of Series A & B Convertible Preferred Stock, net of underwriting discounts (in shares) 1,421,801   1,137,442            
Conversion of Series A & B Convertible Preferred Stock dividends to prefunded warrants and common stock (in shares)         156,713        
Conversion of Series A Convertible Preferred Stock to prefunded warrants (in shares) (1,421,801)                
Conversion of Series B Convertible Preferred Stock to common stock (in shares)     (1,137,442)   11,374,420        
Issuance of common stock in connection with Public offering, net of issuance costs (in shares)         23,625,000        
Issuance of common stock upon exercise of stock options (in shares)         32,778       32,778
Issuance of common stock upon exercise of warrant (in shares)         273,954        
Balance at the end of the period (in shares) at Dec. 31, 2020         59,657,742        
Balance at the beginning of the period at Dec. 31, 2019         $ 24 $ 193,319 $ 76 $ (195,168) $ (1,749)
Increase (Decrease) in Stockholders' Equity                  
Issuance of Series A & B Convertible Preferred Stock, net of underwriting discounts $ 14,062   $ 11,260            
Series A & B Convertible Preferred Stock discount - beneficial conversion feature (5,226) $ 5,226 (4,173) $ 4,173   9,399     9,399
Series A & B Convertible Preferred Stock accrued dividends 207   165     (372)     (372)
Conversion of Series A & B Convertible Preferred Stock dividends to prefunded warrants and common stock (207)   (165)   1 371     372
Conversion of Series A convertible preferred stock to prefunded warrants $ (8,836)         8,836     8,836
Conversion of Series B Convertible Preferred Stock to common stock     $ (7,087)   11 7,076     7,087
Issuance of common stock and prefunded warrants in connection with Public Offering, net of issuance cost         24 48,252     48,276
Issuance of common stock upon exercise of stock options           51     51
Issuance of common stock upon exercise of warrants           348     348
Dividend attributable to the down round feature of 2017 Warrants           303   (303) (303)
Foreign currency translation adjustment             (655)   (655)
Stock-based compensation           2,572     2,572
Net loss               (27,514) (27,514)
Balance at the end of the period at Dec. 31, 2020         $ 60 270,155 (579) (222,985) $ 46,651
Increase (Decrease) in Shares Outstanding                  
Issuance of common stock in connection with Public offering, net of issuance costs (in shares)         27,568,072        
Issuance of common stock upon exercise of stock options (in shares)         2,292       2,292
Issuance of common stock upon exercise of warrant (in shares)         530,643        
Issuance of common stock upon exercise of prefunded warrants (in shares)         559,705        
Balance at the end of the period (in shares) at Dec. 31, 2021         88,318,454        
Increase (Decrease) in Stockholders' Equity                  
Issuance of common stock and prefunded warrants in connection with Public Offering, net of issuance cost         $ 27 96,801     $ 96,828
Issuance of common stock upon exercise of stock options           4     4
Issuance of common stock upon exercise of warrants           993     993
Issuance of common stock upon exercise of prefunded warrants         1 (1)      
Foreign currency translation adjustment             312   312
Stock-based compensation           3,686     3,686
Net loss               (40,587) (40,587)
Balance at the end of the period at Dec. 31, 2021         $ 88 $ 371,638 $ (267) $ (263,572) $ 107,887