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Equity Incentive Plans (Tables) | 9 Months Ended
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Sep. 30, 2022
Equity Incentive Plans |
Schedule of stock option activity under the Equity Plans | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ |  | ​ |  | Weighted |  | ​ |  | ​ | ​
​ | ​ | ​ |  | Average |  | Weighted |  | ​ | Aggregate
​ | ​ | ​ |  | Exercise Price |  | Average Remaining |  | ​ | Intrinsic
​ |  | Options |  | Per Share |  | Life in Years |  | ​ | Value
Outstanding at December 31, 2021 |  | 8,525,618 | ​ | $ | 4.48 |  | 7.58 |  | ​ | ​
Granted | ​ | 3,900,000 | ​ | $ | 1.51 | ​ | ​ | ​ | ​ | ​
Forfeited |  | (492,915) | ​ | $ | 2.17 |  | ​ | ​ | ​ | ​
Outstanding at September 30, 2022 |  | 11,932,703 | ​ | $ | 3.60 |  | 7.65 | ​ | $ | 1
Options exercisable at September 30, 2022 |  | 6,907,653 | ​ | $ | 5.01 |  | 6.39 | ​ | ​ | ​
Options vested and expected to vest at September 30, 2022 |  | 11,932,703 | ​ | $ | 3.60 |  | 7.65 | ​ | $ | 1
Schedule of assumptions used to determine grant-date fair value of stock options | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Nine Months | ​ | Nine Months | ​
​ | ​ | Ended September 30, | ​ | Ended September 30, | ​
​ |  | 2022 |  | 2021 | ​
​ | ​ | ​ | ​ | ​ | ​
Expected volatility | ​ | 82.70 | % | 66.94 | %
Weighted average risk-free interest rate | ​ | 3.06 | % | 0.81 | %
Expected dividend yield | ​ | 0.00 | % | 0.00 | %
Expected term (in years) | ​ | 6.48 | ​ | 6.82 | ​
Schedule of RSU activity under the 2016 Plan | ​
​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | Weighted
​ | ​ | ​ | ​ | Average Grant
​ |  | Number of Shares |  | Date Fair Value
Outstanding at December 31, 2021 |  | 935,606 | ​ | $ | 1.76
Awarded | ​ | 2,650,000 | ​ | $ | 1.93
Outstanding at September 30, 2022 |  | 3,585,606 | ​ | $ | 1.89
Schedule of recognized stock-based compensation expense related to the issuance of stock option awards and RSUs to employees and non-employees in the condensed consolidated statements of operations | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended September 30, | ​ | Nine Months Ended September 30,
​ |  | 2022 |  | 2021 |  | 2022 |  | 2021
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Research and development |  | $ | 634 | ​ | $ | 477 | ​ | $ | 1,805 | ​ | $ | 1,220
General and administrative |  | ​ | 619 | ​ |  | 526 | ​ | ​ | 1,918 | ​ |  | 1,528
Total | ​ | $ | 1,253 | ​ | $ | 1,003 | ​ | $ | 3,723 | ​ | $ | 2,748

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- Definition Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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