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Equity Incentive Plans (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 3 Months Ended | 9 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Jan. 20, 2017 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Dec. 31, 2021 | Jun. 16, 2022
Options |  |  |  |  |  |  |
Outstanding balance at the beginning of the period (in shares) |  |  |  | 8,525,618 |  |  |
Granted (in shares) |  |  |  | 3,900,000 |  |  |
Forfeited (in shares) |  |  |  | (492,915) |  |  |
Outstanding balance at the end of the period (in shares) |  | 11,932,703 |  | 11,932,703 |  | 8,525,618 |
Options exercisable at the end of the period (in shares) |  | 6,907,653 |  | 6,907,653 |  |  |
Options vested and expected to vest at end of period (in shares) |  | 11,932,703 |  | 11,932,703 |  |  |
Weighted Average Exercise Price Per Share |  |  |  |  |  |  |
Outstanding balance at the beginning of the period (in dollars per share) |  |  |  | $ 4.48 |  |  |
Granted (in dollars per share) |  |  |  | 1.51 |  |  |
Forfeited (in dollars per share) |  |  |  | 2.17 |  |  |
Outstanding balance at the end of the period (in dollars per share) |  | $ 3.60 |  | 3.60 |  | $ 4.48 |
Exercisable at the end of the period (in dollars per share) |  | 5.01 |  | 5.01 |  |  |
Options vested and expected to vest at end of the period (in dollars per share) |  | $ 3.60 |  | $ 3.60 |  |  |
Weighted Average Remaining Life in Years |  |  |  |  |  |  |
Outstanding balance |  |  |  | 7 years 7 months 24 days |  | 7 years 6 months 29 days |
Options exercisable at end of period |  |  |  | 6 years 4 months 20 days |  |  |
Options vested and expected to vest at end of the period |  |  |  | 7 years 7 months 24 days |  |  |
Aggregate Intrinsic Value |  |  |  |  |  |  |
Outstanding balance |  | $ 1 |  | $ 1 |  |  |
Options vested and expected to vest at end of the period |  | $ 1 |  | $ 1 |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Expected Volatility |  |  |  | 82.70% | 66.94% |  |
Weighted average risk-free interest rate |  |  |  | 3.06% | 0.81% |  |
Expected dividend yield |  |  |  | 0.00% | 0.00% |  |
Expected term (in years) |  |  |  | 6 years 5 months 23 days | 6 years 9 months 25 days |  |
Options unvested at end of period (in dollars per share) |  | $ 1.10 | $ 1.37 | $ 1.10 | $ 1.37 |  |
Expiration period |  |  |  | 10 years |  |  |
unrecognized compensation cost related to non-vested stock options |  | $ 5,493 |  | $ 5,493 |  |  |
Weighted average period for recognition of compensation cost |  |  |  | 2 years 3 months 21 days |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |
Outstanding at end(in dollars per share) |  | $ 1.10 | $ 1.37 | $ 1.10 | $ 1.37 |  |
Minimum |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Vesting period |  |  |  | 3 years |  |  |
Maximum |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Vesting period |  |  |  | 4 years |  |  |
2016 Plan |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Annual increase in authorized shares (as a percent) | 4.00% |  |  |  |  |  |
Number of options or stock awards available for grant under the Plan |  | 5,382,799 |  | 5,382,799 |  |  |
2022 Plan |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Number of options or stock awards available for grant under the Plan |  |  |  |  |  |  | 7,500,000
Options to purchase common stock |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |
Stock-based compensation expense |  | $ 1,253 | $ 1,003 | $ 3,723 | $ 2,748 |  |
Options to purchase common stock | Research and development |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |
Stock-based compensation expense |  | 634 | 477 | 1,805 | 1,220 |  |
Options to purchase common stock | General and administrative |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |
Stock-based compensation expense |  | 619 | $ 526 | $ 1,918 | $ 1,528 |  |
Restricted stock units to purchase common stock |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Weighted average period for recognition of compensation cost |  |  |  | 2 years 2 months 19 days |  |  |
Aggregate grant fair value |  |  |  | $ 6,777 |  |  |
unrecognized compensation costs related to RSUs granted to employees |  | $ 4,463 |  | $ 4,463 |  |  |
Restricted stock units to purchase common stock | Executive Officer |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] |  |  |  |  |  |  |
Awarded |  |  |  | 2,650,000 | 275,000 |  |
Restricted stock units to purchase common stock | 2016 Plan |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |
Options unvested at end of period (in dollars per share) |  | $ 1.89 |  | $ 1.89 |  | $ 1.76 |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] |  |  |  |  |  |  |
Outstanding at the beginning |  |  |  | 935,606 |  |  |
Awarded |  |  |  | 2,650,000 |  |  |
Outstanding at the end |  | 3,585,606 |  | 3,585,606 |  | 935,606 |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |
Outstanding at beginning( in dollars per share) |  |  |  | $ 1.76 |  |  |
Awarded (in dollars per share) |  |  |  | 1.93 |  |  |
Outstanding at end(in dollars per share) |  | $ 1.89 |  | $ 1.89 |  | $ 1.76 |

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- Definition The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan). + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(2)(i)-(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Fair value of share-based awards for which the grantee gained the right by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Amount by which current fair value of underlying stock exceeds exercise price of fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Number of fully vested and expected to vest options outstanding that can be converted into shares under option plan. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Weighted-average exercise price, at which grantee can acquire shares reserved for issuance, for fully vested and expected to vest options outstanding. Includes, but is not limited to, unvested options for which requisite service period has not been rendered but that are expected to vest based on achievement of performance condition, if forfeitures are recognized when they occur. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated. + References No definition available. + Details
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- Definition Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options. + References No definition available. + Details
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- Definition Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (a)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Expected term of award under share-based payment arrangement, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2)(i) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.D.2) -URI http://asc.fasb.org/extlink&oid=122041274&loc=d3e301413-122809 + Details
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