    <SEC-DOCUMENT>0001104659-22-052351-index.html : 20220428
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    <ACCEPTANCE-DATETIME>20220428164543
    ACCESSION NUMBER:		0001104659-22-052351
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		3
    FILED AS OF DATE:		20220428
    DATE AS OF CHANGE:		20220428

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LEAP THERAPEUTICS, INC.
    		CENTRAL INDEX KEY:			0001509745
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				274412575
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-37990
    		FILM NUMBER:		22867470

    	BUSINESS ADDRESS:
    		STREET 1:		47 THORNDIKE STREET
    		STREET 2:		SUITE B1-1
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142
    		BUSINESS PHONE:		617 252 4343

    	MAIL ADDRESS:
    		STREET 1:		47 THORNDIKE STREET
    		STREET 2:		SUITE B1-1
    		CITY:			CAMBRIDGE
    		STATE:			MA
    		ZIP:			02142

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Dekkun Corp
    		DATE OF NAME CHANGE:	20110107
    </SEC-HEADER>
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    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>tm223513d2_defa14a.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
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    <SEQUENCE>2
    <FILENAME>tm223513d2_defa14aimg001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: tm223513d2_defa14aimg001.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>tm223513d2_defa14aimg002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: tm223513d2_defa14aimg002.jpg

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