<SEC-DOCUMENT>0001104659-22-052351-index.html : 20220428
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<ACCEPTANCE-DATETIME>20220428164543
ACCESSION NUMBER:		0001104659-22-052351
CONFORMED SUBMISSION TYPE:	DEFA14A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20220428
DATE AS OF CHANGE:		20220428

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			LEAP THERAPEUTICS, INC.
		CENTRAL INDEX KEY:			0001509745
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				274412575
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEFA14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37990
		FILM NUMBER:		22867470

	BUSINESS ADDRESS:	
		STREET 1:		47 THORNDIKE STREET
		STREET 2:		SUITE B1-1
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617 252 4343

	MAIL ADDRESS:	
		STREET 1:		47 THORNDIKE STREET
		STREET 2:		SUITE B1-1
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Dekkun Corp
		DATE OF NAME CHANGE:	20110107
</SEC-HEADER>
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<SEQUENCE>1
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Document 1 - file: tm223513d2_defa14a.htm

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<SEQUENCE>2
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Document 2 - file: tm223513d2_defa14aimg001.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>tm223513d2_defa14aimg002.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: tm223513d2_defa14aimg002.jpg

</DOCUMENT>
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