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Equity Incentive Plans (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Jan. 20, 2017 | Sep. 30, 2024 | Sep. 30, 2023 | Sep. 30, 2024 | Sep. 30, 2023 | Dec. 31, 2023 | Jul. 02, 2024 | Jun. 16, 2023 | Jun. 16, 2022
Options |  |  |  |  |  |  |  |  |
Outstanding balance at the beginning of the period (in shares) |  |  |  | 3,384,366 |  |  |  |  |
Granted (in shares) |  |  |  | 1,727,500 |  |  |  |  |
Exercised (in shares) |  |  |  | (10,557) |  |  |  |  |
Forfeited (in shares) |  |  |  | (254,674) |  |  |  |  |
Outstanding balance at the end of the period (in shares) |  | 4,846,635 |  | 4,846,635 |  | 3,384,366 |  |  |
Options exercisable at the end of the period (in shares) |  | 2,396,563 |  | 2,396,563 |  |  |  |  |
Options vested and expected to vest at end of period (in shares) |  | 4,846,635 |  | 4,846,635 |  |  |  |  |
Weighted Average Exercise Price Per Share |  |  |  |  |  |  |  |  |
Outstanding balance at the beginning of the period (in dollars per share) |  |  |  | $ 13.97 |  |  |  |  |
Granted (in dollars per share) |  |  |  | 2.67 |  |  |  |  |
Exercised (in dollars per share) |  |  |  | 2.77 |  |  |  |  |
Forfeited (in dollars per share) |  |  |  | 5.69 |  |  |  |  |
Outstanding balance at the end of the period (in dollars per share) |  | $ 10.40 |  | 10.40 |  | $ 13.97 |  |  |
Options exercisable at the end of the period (in dollars per share) |  | 17.90 |  | 17.90 |  |  |  |  |
Options vested and expected to vest at end of the period (in dollars per share) |  | $ 10.40 |  | $ 10.40 |  |  |  |  |
Weighted Average Remaining Life in Years |  |  |  |  |  |  |  |  |
Outstanding balance |  |  |  | 8 years 2 months 26 days |  | 8 years 4 months 24 days |  |  |
Options exercisable at end of period |  |  |  | 7 years 4 months 24 days |  |  |  |  |
Options vested and expected to vest at end of the period |  |  |  | 8 years 2 months 26 days |  |  |  |  |
Aggregate Intrinsic Value |  |  |  |  |  |  |  |  |
Outstanding balance |  | $ 527 |  | $ 527 |  | $ 3,431 |  |  |
Options vested and expected to vest at end of the period |  | 527 |  | $ 527 |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Expected volatility |  |  |  | 92.99% | 90.37% |  |  |  |
Weighted average risk-free interest rate |  |  |  | 3.98% | 4.05% |  |  |  |
Expected dividend yield |  |  |  | 0.00% | 0.00% |  |  |  |
Expected term (in years) |  |  |  | 6 years 5 months 15 days | 6 years 5 months 23 days |  |  |  |
Expiration period |  |  |  | 10 years |  |  |  |  |
Unrecognized compensation cost related to non-vested stock options |  | 5,633 |  | $ 5,633 |  |  |  |  |
Weighted average period for recognition of compensation cost |  |  |  | 1 year 11 months 4 days |  |  |  |  |
Minimum |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Vesting period |  |  |  | 3 years |  |  |  |  |
Maximum |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Vesting period |  |  |  | 4 years |  |  |  |  |
Options to purchase common stock |  |  |  |  |  |  |  |  |
Weighted Average Exercise Price Per Share |  |  |  |  |  |  |  |  |
Granted (in dollars per share) |  |  |  | $ 2.12 | $ 2.09 |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |  |  |
Stock Based Compensation Expense |  | 1,339 | $ 1,300 | $ 3,957 | $ 3,875 |  |  |  |
Options to purchase common stock | Research and development |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |  |  |
Stock Based Compensation Expense |  | 720 | 737 | 2,076 | 2,086 |  |  |  |
Options to purchase common stock | General and administrative |  |  |  |  |  |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |  |  |
Stock Based Compensation Expense |  | 619 | $ 563 | $ 1,881 | $ 1,789 |  |  |  |
Restricted stock units to purchase common stock |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Weighted average period for recognition of compensation cost |  |  |  | 4 months 17 days |  |  |  |  |
Vested |  |  |  | $ 4,388 |  |  |  |  |
Unrecognized compensation costs related to RSUs granted to employees |  | $ 516 |  | $ 516 |  |  |  |  |
2016 Plan |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Annual increase in authorized shares (as a percent) | 4.00% |  |  |  |  |  |  |  |
2016 Plan | Restricted stock units to purchase common stock |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Options unvested at end of period (in dollars per share) |  | $ 19.29 |  | $ 19.29 |  | $ 19.97 |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] |  |  |  |  |  |  |  |  |
Outstanding at the beginning |  |  |  | 262,500 |  |  |  |  |
Vested (in shares) |  |  |  | (27,500) |  |  |  |  |
Forfeited (in shares) |  |  |  | (7,500) |  |  |  |  |
Outstanding at the end |  | 227,500 |  | 227,500 |  | 262,500 |  |  |
Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Non vested, Weighted Average Grant Date Fair Value |  |  |  |  |  |  |  |  |
Outstanding at beginning( in dollars per share) |  |  |  | $ 19.97 |  |  |  |  |
Vested(in dollars per share) |  |  |  | 25.70 |  |  |  |  |
Forfeited (in dollars per share) |  |  |  | 19.40 |  |  |  |  |
Outstanding at end(in dollars per share) |  | $ 19.29 |  | $ 19.29 |  | $ 19.97 |  |  |
2022 Plan |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Common shares reserved for issuance |  |  |  |  |  |  | 2,000,000 | 2,250,000 |
Number of options or stock awards available for grant under the Plan |  |  |  |  |  |  |  |  | 750,000
2016 and 2022 Plan |  |  |  |  |  |  |  |  |
Assumptions used to determine grant-date fair value |  |  |  |  |  |  |  |  |
Number of options or stock awards available for grant under the Plan |  | 2,573,313 |  | 2,573,313 |  |  |  |  |

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- Definition Weighted average fair value as of the grant date of equity-based award plans other than stock (unit) option plans that were not exercised or put into effect as a result of the occurrence of a terminating event. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(03) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Per share or unit weighted-average fair value of nonvested award under share-based payment arrangement. Excludes share and unit options. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(2)(i) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(2)(ii) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The number of equity-based payment instruments, excluding stock (or unit) options, that vested during the reporting period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(2)(iii)(02) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Fair value of share-based awards for which the grantee gained the right by satisfying service and performance requirements, to receive or retain shares or units, other instruments, or cash. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (d)(2) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (f)(2)(iii) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (f)(2)(ii) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iii) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(03) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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- Definition Gross number of share options (or share units) granted during the period. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 718 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 2 -Subparagraph (c)(1)(iv)(01) -Publisher FASB -URI https://asc.fasb.org/1943274/2147480429/718-10-50-2 + Details
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