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v3.19.1

Consolidated Statements of Operations - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Revenue: |  |  |
Total revenue | $ 625 | $ 479 | $ 576
Costs and expenses: |  |  |
Cost of goods sold | 517 | 690 | 746
Research and development | 8,453 | 5,799 | 3,330
Selling, general and administrative | 5,757 | 6,395 | 4,108
Total costs and expenses | 14,727 | 12,884 | 8,184
Operating loss | (14,102) | (12,405) | (7,608)
Other income (expense): |  |  |
Interest income | 118 | 95 |
Interest expense |  |  | (1,736)
Change in fair value of convertible preferred stock warrant liability |  |  | 250
Change in fair value of maturity date preferred stock warrant liability |  |  | 10
Change in fair value of convertible shareholder notes derivative liability |  |  | (1,224)
Other expense | (3) | 2 | (2)
Other income (expense), net | 115 | 97 | (2,702)
Net loss | $ (13,987) | $ (12,308) | $ (10,310)
Net loss per share, basic and diluted (in dollars per share) | $ (0.36) | $ (0.32) | $ (1.23)
Weighted-average shares used in computing net loss per share, basic and diluted (in shares) | 38,377,606 | 38,160,543 | 8,368,284
Product [Member] |  |  |
Revenue: |  |  |
Total revenue | $ 282 | $ 389 | $ 517
Collaboration Agreement [Member] |  |  |
Revenue: |  |  |
Total revenue | $ 343 | $ 90 | $ 59

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