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Note 8 - Stockholders' Equity (Details Textual) |  |  |  |  |  |  |  |  |  | 12 Months Ended |  |
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Dec. 02, 2024 USD ($) | Sep. 03, 2024 USD ($) $ / shares shares | Aug. 29, 2024 $ / shares shares | May 30, 2024 | Feb. 09, 2024 USD ($) $ / shares shares | Dec. 06, 2023 USD ($) | Nov. 16, 2023 USD ($) $ / shares shares | Jun. 21, 2023 USD ($) $ / shares shares | Apr. 12, 2022 USD ($) | Dec. 31, 2024 USD ($) $ / shares shares | Dec. 31, 2023 USD ($) $ / shares shares | Sep. 30, 2024 USD ($) | Dec. 31, 2022 $ / shares
Common Stock, Shares Authorized (in shares) | shares |  |  |  |  |  |  |  |  |  | 50,000,000 | 100,000,000 |  |
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares |  |  |  |  |  |  |  |  |  | $ 0.001 | $ 0.001 |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  |  |  |  |  |  |  | $ 3.1 | $ 94.5 |  | $ 95.4
Payments of Stock Issuance Costs |  |  |  |  |  |  |  |  |  | $ 1,252,000 | $ 662,000 |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  |  |  |  | $ 10,552,000 | $ 4,388,000 |  |
Common Warrants With Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares |  | 2,400,000 | 1,377,990 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  | $ 3 | $ 3 |  |  |  |  |  |  |  |  |  |
Common Warrants Issued With Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares |  |  | 1,022,010 |  |  |  |  |  |  |  |  |  |
Prefunded Warrants [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares |  |  | 1,022,010 |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  | $ 2.999 |  |  |  |  |  |  |  |  |  |
Warrants To Purchase Common Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Class of Warrant or Right, Number of Securities Called by Warrants or Rights | shares |  |  |  |  | 67,104 |  |  |  |  |  |  |  |
Class of Warrant or Right, Exercise Price of Warrants or Rights | $ / shares |  |  |  |  | $ 6.6 |  |  |  |  |  |  |  |
Common Stock In 2024 Agreement [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  | 1,377,990 |  |  |  |  |  |  |  |  |  |
Common Stock, Par or Stated Value Per Share (in dollars per share) | $ / shares |  |  | $ 0.001 |  |  |  |  |  |  |  |  |  |
September 2024 Financing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity |  | $ 7,200,000 |  |  |  |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  | $ 926,000 |  |  |  |  |  |  |  |  |  |  |
September 2024 Financing [Member] | Company Directors and Executive Officers [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  |  |  |  |  |  | 211,000 |  |  |
Common Warrants With Stock [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  | 2,400,000 |  |  |  |  |  |  |  |  |  |  |
February 2024 Financing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  | 134,199 |  |  |  |  |  |  |  |
Proceeds from Issuance or Sale of Equity |  |  |  |  | $ 875,000 |  |  |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  | $ 43,000 |  |  |  |  |  |  |  |
November 2023 Financing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  |  |  | 133,333 |  |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  | $ 312,000 |  |  |  |  |  |
Shares Issued, Price Per Share (in dollars per share) | $ / shares |  |  |  |  |  |  | $ 9.75 |  |  |  |  |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  | $ 1,300,000 |  |  |  |  |  |
June 2023 Financing [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  |  |  |  | 75,543 |  |  |  |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  |  | $ 194,000 |  |  |  |  |
Shares Issued, Price Per Share (in dollars per share) | $ / shares |  |  |  |  |  |  |  | $ 35.04 |  |  |  |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  |  | $ 2,600,000 |  |  |  |  |
June 2023 Financing [Member] | Company’s Directors and Executive Officers [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  |  |  |  | 13,556 |  |  |  |  |
Sales Agreement with Cantor Fitzgerald Co (Cantor) [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stock Issued During Period, Shares, New Issues | shares |  |  |  |  |  |  |  |  |  | 428,864 | 14,349 |  |
Payments of Stock Issuance Costs |  |  |  |  |  |  |  |  |  | $ 94,000 | $ 179,000 |  |
Proceeds from Issuance of Common Stock |  |  |  |  |  |  |  |  |  | 2,500,000 | $ 441,000 |  |
Sale of Stock, Aggregate Value, Maximum |  |  |  |  |  |  |  |  | $ 10,500,000 |  |  |  |
Accrued Sales Commission, Current, Percentage |  |  |  |  |  |  |  |  | 3.00% |  |  |  |
Sales Agreement With H.C. Wainwright & Co., LLC [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Sale of Stock, Aggregate Value, Maximum | $ 1,300,000 |  |  |  |  | $ 2,750,000 |  |  |  |  |  |  |
Accrued Sales Commission, Current, Percentage |  |  |  |  |  | 3.00% |  |  |  |  |  |  |
Sale of Stock, Available Value |  |  |  |  |  |  |  |  |  | $ 1,300,000 |  | $ 264,000 |
Reverse Stock Split [Member] |  |  |  |  |  |  |  |  |  |  |  |  |
Stockholders' Equity Note, Stock Split, Conversion Ratio |  |  |  | 15 |  |  |  |  |  |  |  |  |

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