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Note 8 - Share-based Compensation (Tables)

9 Months Ended

Sep. 30, 2025

Notes Tables

Schedule of Share-based Compensation, Expense [Table Text Block]

		Three months ended								Nine months ended
		September 30,								September 30,
		2025				2024				2025				2024
Research and development		$	42			$	98			$	192			$	315
Selling, general and administrative			35				79				153				250
Total share-based compensation		$	77			$	177			$	345			$	565

Share-Based Payment Arrangement, Option, Activity [Table Text Block]

		Number of shares				Weighted average exercise price				Weighted average remaining contractual term (years)				Aggregate intrinsic value (in thousands)
Balance, December 31, 2024			168,184			$	47.97				6.6			$	—
Stock options forfeited			(3,284	)			38.15
Balance, September 30, 2025			164,900			$	48.17				5.8			$	—
Exercisable, September 30, 2025			134,909			$	55.74				5.2			$	—

Schedule of Nonvested Restricted Stock Units Activity [Table Text Block]

						Weighted
						average
						grant date
		Number of				fair value
		shares				per share
Balance, December 31, 2024			—			$	n/a
RSUs granted			1,000				2.09
RSUs released			(1,000	)			2.09
Balance, September 30, 2025			—			$	n/a

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