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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016
Expenses
Research and development	$ 8,956,468	$ 5,852,121	$ 23,714,932	$ 13,941,283
General and administrative	2,450,588	2,379,809	7,922,738	7,012,057
Total expenses	11,407,056	8,231,930	31,637,670	20,953,340
Loss from operations	(11,407,056)	(8,231,930)	(31,637,670)	(20,953,340)
Foreign exchange losses	(9,417)	(2,578)	(46,215)	(27,552)
Investment income	293,797	69,983	508,116	136,960
Interest expense	(137,899)	(258,764)	(509,526)	(797,376)
Net loss	$ (11,260,575)	$ (8,423,289)	$ (31,685,295)	$ (21,641,308)
Net loss per share, basic and diluted	$ (0.28)	$ (0.24)	$ (0.84)	$ (0.71)
Weighted average shares outstanding, basic and diluted	40,880,359	34,806,263	37,676,686	30,393,293

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The amount of net income or loss for the period per each share in instances when basic and diluted earnings per share are the same amount and reported as a single line item on the face of the financial statements. Basic earnings per share is the amount of net income or loss for the period per each share of common stock or unit outstanding during the reporting period. Diluted earnings per share includes the amount of net income or loss for the period available to each share of common stock or common unit outstanding during the reporting period and to each share or unit that would have been outstanding assuming the issuance of common shares or units for all dilutive potential common shares or units outstanding during the reporting period.

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