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Condensed Consolidated Statement of Changes in Stockholders' Equity (Unaudited) - USD ($)
Total
Public Offering
Private Placement
Common Stock
Common Stock
Public Offering
Common Stock
Private Placement
Additional Paid-in Capital
Additional Paid-in Capital
Public Offering
Additional Paid-in Capital
Private Placement
Accumulated Deficit
Balance at Dec. 31, 2015 $ 55,319,557     $ 2,472     $ 157,129,947     $ (101,812,862)
Balance (in shares) at Dec. 31, 2015       24,721,143            
Exercise of common stock warrants 22,222,494     $ 385     22,222,109      
Exercise of common stock warrants (in shares)       3,850,051            
Exercise of stock options 9,861           9,861      
Exercise of stock options (in shares)       1,900            
Issuance of common stock, net of issuance costs   $ 53,667,991 $ 999,999   $ 606 $ 18   $ 53,667,385 $ 999,981  
Issuance of common stock, net of issuance costs (in shares)         6,052,631 181,488        
Stock-based compensation 2,558,456           2,558,456      
Net loss (21,641,308)                 (21,641,308)
Balance at Sep. 30, 2016 113,137,050     $ 3,481     236,587,739     (123,454,170)
Balance (in shares) at Sep. 30, 2016       34,807,213            
Balance at Dec. 31, 2016 $ 105,982,208     $ 3,502     238,836,940     (132,858,234)
Balance (in shares) at Dec. 31, 2016 35,024,002     35,024,002            
Exercise of common stock warrants $ 9,356,833     $ 162     9,356,671      
Exercise of common stock warrants (in shares)       1,621,073            
Exercise of stock options $ 1,130,544     $ 20     1,130,524      
Exercise of stock options (in shares) 197,874     197,874            
Issuance of common stock, net of issuance costs   $ 41,618,332     $ 575     $ 41,617,757    
Issuance of common stock, net of issuance costs (in shares)         5,750,000          
Repurchase of common stock $ (389)     $ (389)            
Repurchase of common stock (in shares)       (3,892,256)            
Stock-based compensation 3,775,469           3,775,469      
Net loss (31,685,295)                 (31,685,295)
Balance at Sep. 30, 2017 $ 130,177,702     $ 3,870     $ 294,717,361     $ (164,543,529)
Balance (in shares) at Sep. 30, 2017 38,700,693     38,700,693