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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Cash flows from operating activities:    
Net loss $ (15,827,200) $ (12,418,263)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 4,367 4,367
Amortization of debt discount recorded as interest expense   24,252
Accretion of marketable securities premium (242,708) (54,212)
Amortization of right-of-use assets 34,622  
Stock-based compensation expense 2,461,699 2,113,936
Changes in operating assets and liabilities    
Prepaid expenses and other current assets 851,715 (2,944,222)
Accounts payable 1,225,897 1,389,295
Accrued expenses and other current liabilities 1,911,423 952,720
Operating lease liabilities, current 20,609  
Other noncurrent liabilities   395
Operating lease liabilities, noncurrent (41,016)  
Net cash used in operating activities (9,600,592) (10,931,732)
Cash flows from investing activities:    
Proceeds from the maturity and redemption of marketable securities 9,000,000 39,250,000
Purchase of marketable securities (19,551,411) (7,934,482)
Net cash (used in) provided by investing activities (10,551,411) 31,315,518
Cash flows from financing activities:    
Proceeds from exercise of stock options 525,000  
Repayments of notes payable   (1,289,882)
Net cash provided (used in) by financing activities 525,000 (1,289,882)
Net (decrease) increase in cash, cash equivalents and restricted cash (19,627,003) 19,093,904
Cash, cash equivalents and restricted cash    
Beginning of period 50,334,871 26,131,821
End of period 30,707,868 45,225,725
Supplemental disclosure of cash flow information    
Cash paid for interest   53,975
Reconciliation of the Condensed Consolidated Statements of Cash Flows to the Condensed Consolidated Balance Sheets    
Cash and cash equivalents 30,607,868 45,125,725
Restricted cash 100,000 100,000
Total cash, cash equivalents and restricted cash $ 30,707,868 $ 45,225,725