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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)	Total	Common Stock	Additional Paid-in Capital	Accumulated Deficit
Balance at Dec. 31, 2018	$ 90,264,769	$ 3,894	$ 304,813,603	$ (214,552,728)
Balance (in shares) at Dec. 31, 2018		38,937,971
Exercise of stock options	525,000	$ 9	524,991
Exercise of stock options (in shares)		87,500
Stock-based compensation	2,461,699		2,461,699
Net loss	(15,827,200)			(15,827,200)
Balance at Mar. 31, 2019	77,424,268	$ 3,903	307,800,293	(230,379,928)
Balance (in shares) at Mar. 31, 2019		39,025,471
Balance at Dec. 31, 2019	$ 27,779,543	$ 3,908	314,511,853	(286,736,218)
Balance (in shares) at Dec. 31, 2019	39,084,121	39,084,121
Exercise of stock options	$ 797,629	$ 14	797,615
Exercise of stock options (in shares)		135,013
Stock-based compensation	2,198,187		2,198,187
Net loss	(12,151,165)			(12,151,165)
Balance at Mar. 31, 2020	$ 18,624,194	$ 3,922	$ 317,507,655	$ (298,887,383)
Balance (in shares) at Mar. 31, 2020	39,219,134	39,219,134

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Amount of increase to additional paid-in capital (APIC) for recognition of cost for award under share-based payment arrangement.

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