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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 9 Months Ended 194 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Revenues:          
Collaboration and research and development revenue         $ 3,100
Grant revenue 38   64   3,712
Total revenues 38   64   6,812
Operating expenses:          
Research and development 1,532 2,066 4,596 7,005 190,395
General and administrative 2,028 1,814 5,917 5,136 86,748
Goodwill and intangible impairment         2,747
Restructuring costs         2,634
Total operating expenses 3,560 3,880 10,513 12,141 282,524
Operating loss (3,522) (3,880) (10,449) (12,141) (275,712)
Other income (expense):          
Costs associated with aborted 2004 IPO         (3,550)
Payment under guarantee         (1,652)
Change in valuation of Economic Rights (63)   27   27
Change in valuation of other liabilities measured at fair value 1 440 51 643 6,378
Foreign exchange (losses)/gains 6 28 237 (59) (4,060)
Interest income 5 9 17 33 13,742
Interest expense         (4,567)
Other income 1   77   77
Total other income (expense) (50) 477 409 617 6,395
Loss from continuing operations before taxes (3,572) (3,403) (10,040) (11,524) (269,317)
Income tax benefit 419 126 714 443 19,158
Net loss from continuing operations (3,153) (3,277) (9,326) (11,081) (250,159)
Discontinued operations:          
Income (loss) from discontinued operations, net of tax of $0 for all periods presented 1,263 (168) 904 (504) (11,812)
Net loss (1,890) (3,445) (8,422) (11,585) (261,971)
Dividends on preferred ordinary shares         (38,123)
Deemed dividend on convertible exchangeable preferred shares         (3,515)
Dividend on convertible exchangeable preferred shares (182) (182) (546) (546) (4,203)
Net loss applicable to common shareholders $ (2,072) $ (3,627) $ (8,968) $ (12,131) $ (307,812)
Net loss per share, continuing operations          
Basic and diluted (in dollars per share) $ (0.37) $ (0.43) $ (1.13) $ (1.58)  
Net income (loss) per share, discontinued operations          
Basic and diluted (in dollars per share) $ 0.15 $ (0.02) $ 0.11 $ (0.07)  
Net loss per share - Basic and diluted (in dollars per share) $ (0.25) $ (0.47) $ (1.09) $ (1.73)  
Weighted average common shares outstanding (in shares) 8,429,269 7,673,096 8,227,721 6,997,391