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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $) | Total | Preferred Stock | Common stock | Additional paid-in capital | Accumulated other comprehensive income/(loss) | Deferred compensation | Deficit accumulated during development stage | Comprehensive loss
--- | --- | --- | --- | --- | --- | --- | --- | ---
Balance at Aug. 12, 1996 |  |  |  |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | $ 1,000 |  |  | $ 1,000 |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (4,000) |  |  |  | (4,000) |  |  | (4,000)
Loss for the year | (290,000) |  |  |  |  |  | (290,000) | (290,000)
Comprehensive loss | (294,000) |  |  |  |  |  |  | (294,000)
Balance at Mar. 31, 1997 | (293,000) |  |  | 1,000 | (4,000) |  | (290,000) |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 4,217,000 |  |  | 4,217,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 38,111 |  |  |  |  |
Issue of shares for IP rights agreement, research & development agreement and license agreement | 262,000 |  |  | 262,000 |  |  |  |
Stock-based compensation |  |  |  | 2,002,000 |  | (2,002,000) |  |
Amortization of deferred stock-based compensation | 302,000 |  |  |  |  | 302,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | 55,000 |  |  |  | 55,000 |  |  | 55,000
Loss for the year | (2,534,000) |  |  |  |  |  | (2,534,000) | (2,534,000)
Comprehensive loss | (2,479,000) |  |  |  |  |  |  | (2,479,000)
Balance at Mar. 31, 1998 | 2,009,000 |  |  | 6,482,000 | 51,000 | (1,700,000) | (2,824,000) |
Balance (in shares) at Mar. 31, 1998 |  |  | 38,111 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Amortization of deferred stock-based compensation | 406,000 |  |  |  |  | 406,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | 11,000 |  |  |  | 11,000 |  |  | 11,000
Loss for the year | (3,964,000) |  |  |  |  |  | (3,964,000) | (3,964,000)
Comprehensive loss | (3,953,000) |  |  |  |  |  |  | (3,953,000)
Balance at Mar. 31, 1999 | (1,538,000) |  |  | 6,482,000 | 62,000 | (1,294,000) | (6,788,000) |
Balance (in shares) at Mar. 31, 1999 |  |  | 38,111 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 12,717,000 |  |  | 12,717,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 76,984 |  |  |  |  |
Issue of shares on conversion of bridging loan and Loan Note Instrument | 1,638,000 |  |  | 1,638,000 |  |  |  |
Issue of shares on conversion of bridging loan and Loan Note Instrument (in shares) |  |  | 12,943 |  |  |  |  |
Issue of shares in lieu of cash bonus | 164,000 |  |  | 164,000 |  |  |  |
Issue of shares in lieu of cash bonus (in shares) |  |  | 1,294 |  |  |  |  |
Issue of shares for IP rights agreement, research & development agreement and license agreement | 409,000 |  |  | 409,000 |  |  |  |
Issue of common stock upon exercise of stock options | 40,000 |  |  | 40,000 |  |  |  |
Issue of common stock upon exercise of stock options (in shares) |  |  | 324 |  |  |  |  |
Stock-based compensation |  |  |  | 167,000 |  | (167,000) |  |
Amortization of deferred stock-based compensation | 433,000 |  |  |  |  | 433,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (194,000) |  |  |  | (194,000) |  |  | (194,000)
Loss for the year | (5,686,000) |  |  |  |  |  | (5,686,000) | (5,686,000)
Comprehensive loss | (5,880,000) |  |  |  |  |  |  | (5,880,000)
Balance at Mar. 31, 2000 | 7,983,000 |  |  | 21,617,000 | (132,000) | (1,028,000) | (12,474,000) |
Balance (in shares) at Mar. 31, 2000 |  |  | 129,656 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Stock-based compensation |  |  |  | 294,000 |  | (294,000) |  |
Amortization of deferred stock-based compensation | 275,000 |  |  |  |  | 275,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (466,000) |  |  |  | (466,000) |  |  | (466,000)
Loss for the year | (10,382,000) |  |  |  |  |  | (10,382,000) | (10,382,000)
Comprehensive loss | (10,848,000) |  |  |  |  |  |  | (10,848,000)
Balance at Mar. 31, 2001 | (2,590,000) |  |  | 21,911,000 | (598,000) | (1,047,000) | (22,856,000) |
Balance (in shares) at Mar. 31, 2001 |  |  | 129,656 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 779 |  |  |  |  |
Issue of warrants in connection with registered direct offering | 1,215,000 |  |  | 1,215,000 |  |  |  |
Issue of shares for IP rights agreement, research & development agreement and license agreement | 183,000 |  |  | 183,000 |  |  |  |
Issue of shares for IP rights agreement, research & development agreement and license agreement (in shares) |  |  | 644 |  |  |  |  |
Issue of common stock upon exercise of stock options | 106,000 |  |  | 106,000 |  |  |  |
Stock-based compensation |  |  |  | 363,000 |  | (363,000) |  |
Amortization of deferred stock-based compensation | 672,000 |  |  |  |  | 672,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | 191,000 |  |  |  | 191,000 |  |  | 191,000
Loss for the year | (14,853,000) |  |  |  |  |  | (14,853,000) | (14,853,000)
Comprehensive loss | (14,662,000) |  |  |  |  |  |  | (14,662,000)
Balance at Mar. 31, 2002 | (15,076,000) |  |  | 23,778,000 | (407,000) | (738,000) | (37,709,000) |
Balance (in shares) at Mar. 31, 2002 |  |  | 131,079 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock upon exercise of stock options | 12,000 |  |  | 12,000 |  |  |  |
Stock-based compensation |  |  |  | (84,000) |  | 84,000 |  |
Amortization of deferred stock-based compensation | 305,000 |  |  |  |  | 305,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (1,846,000) |  |  |  | (1,846,000) |  |  | (1,846,000)
Loss for the year | (15,542,000) |  |  |  |  |  | (15,542,000) | (15,542,000)
Comprehensive loss | (17,388,000) |  |  |  |  |  |  | (17,388,000)
Balance at Mar. 31, 2003 | (32,147,000) |  |  | 23,706,000 | (2,253,000) | (349,000) | (53,251,000) |
Balance (in shares) at Mar. 31, 2003 |  |  | 131,079 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 27,635,000 |  |  | 27,635,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 215,755 |  |  |  |  |
Preferred stock conversions | 58,148,000 |  | 1,000 | 58,147,000 |  |  |  |
Preferred stock conversions (in shares) |  |  | 538,449 |  |  |  |  |
Issue of common stock upon exercise of stock options | 115,000 |  |  | 115,000 |  |  |  |
Issue of common stock upon exercise of stock options (in shares) |  |  | 936 |  |  |  |  |
Amortization of deferred stock-based compensation | 217,000 |  |  |  |  | 217,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (1,343,000) |  |  |  | (1,343,000) |  |  | (1,343,000)
Loss for the year | (14,977,000) |  |  |  |  |  | (14,977,000) | (14,977,000)
Comprehensive loss | (16,320,000) |  |  |  |  |  |  | (16,320,000)
Balance at Dec. 31, 2003 | 37,648,000 |  | 1,000 | 109,603,000 | (3,596,000) | (132,000) | (68,228,000) |
Balance (in shares) at Dec. 31, 2003 |  |  | 886,219 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 8,541,000 |  |  | 8,541,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 61,510 |  |  |  |  |
Warrant exercise (in shares) |  |  | 3,233 |  |  |  |  |
Stock-based compensation | (1,918,000) |  |  | (2,050,000) |  | 132,000 |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | 2,424,000 |  |  |  | 2,424,000 |  |  | 2,424,000
Loss for the year | (22,742,000) |  |  |  |  |  | (22,742,000) | (22,742,000)
Comprehensive loss | (20,318,000) |  |  |  |  |  |  | (20,318,000)
Balance at Dec. 31, 2004 | 23,953,000 |  | 1,000 | 116,094,000 | (1,172,000) |  | (90,970,000) |
Balance (in shares) at Dec. 31, 2004 |  |  | 950,962 |  |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (1,786,000) |  |  |  | (1,786,000) |  |  | (1,786,000)
Loss for the year | (18,048,000) |  |  |  |  |  | (18,048,000) | (18,048,000)
Comprehensive loss | (19,834,000) |  |  |  |  |  |  | (19,834,000)
Balance at Dec. 31, 2005 | 4,119,000 |  | 1,000 | 116,094,000 | (2,958,000) |  | (109,018,000) |
Balance (in shares) at Dec. 31, 2005 |  |  | 950,962 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares) |  |  | 92,630 |  |  |  |  |
Issue of shares on conversion of bridging loan and Loan Note Instrument (in shares) |  |  | 65,187 |  |  |  |  |
Reverse Acquisition | 16,255,000 | 2,000 |  | 16,253,000 |  |  |  |
Reverse Acquisition (in shares) |  | 2,046,813 | 281,133 |  |  |  |  |
Loan from Cyclacel Group plc waived | 10,420,000 |  |  | 10,420,000 |  |  |  |
Issue of common stock and warrants for cash | 42,362,000 |  | 1,000 | 42,361,000 |  |  |  |
Issue of common stock and warrants for cash (in shares) |  |  | 918,367 |  |  |  |  |
Stock-based compensation | 9,600,000 |  |  | 9,600,000 |  |  |  |
Change in unrealized loss on investment | 5,000 |  |  |  | 5,000 |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | 416,000 |  |  |  | 416,000 |  |  | 416,000
Loss for the year | (29,258,000) |  |  |  |  |  | (29,258,000) | (29,258,000)
Comprehensive loss | (28,842,000) |  |  |  |  |  |  | (28,842,000)
Balance at Dec. 31, 2006 | 53,919,000 | 2,000 | 2,000 | 194,728,000 | (2,537,000) |  | (138,276,000) |
Balance (in shares) at Dec. 31, 2006 |  | 2,046,813 | 2,308,279 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 33,357,000 |  | 1,000 | 33,356,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 607,095 |  |  |  |  |
Issue of warrants in connection with registered direct offering | (6,750,000) |  |  | (6,750,000) |  |  |  |
Issue of common stock upon exercise of stock options | 163,000 |  |  | 163,000 |  |  |  |
Issue of common stock upon exercise of stock options (in shares) |  |  | 3,644 |  |  |  |  |
Stock-based compensation | 1,733,000 |  |  | 1,733,000 |  |  |  |
Preferred stock dividends declared | (307,000) |  |  | (307,000) |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Translation adjustment | (93,000) |  |  |  | (93,000) |  |  | (93,000)
Loss for the year | (24,053,000) |  |  |  |  |  | (24,053,000) | (24,053,000)
Comprehensive loss | (24,146,000) |  |  |  |  |  |  | (24,146,000)
Balance at Dec. 31, 2007 | 57,969,000 | 2,000 | 3,000 | 222,923,000 | (2,630,000) |  | (162,329,000) |
Balance (in shares) at Dec. 31, 2007 |  | 2,046,813 | 2,919,018 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Stock-based compensation | 1,698,000 |  |  | 1,698,000 |  |  |  |
Preferred stock dividends declared | (1,227,000) |  |  | (1,227,000) |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Unrealized foreign exchange on intercompany loans | (12,330,000) |  |  |  | (12,330,000) |  |  | (12,330,000)
Translation adjustment | 14,918,000 |  |  |  | 14,918,000 |  |  | 14,918,000
Loss for the year | (40,386,000) |  |  |  |  |  | (40,386,000) | (40,386,000)
Comprehensive loss | (37,798,000) |  |  |  |  |  |  | (37,798,000)
Balance at Dec. 31, 2008 | 20,642,000 | 2,000 | 3,000 | 223,394,000 | (42,000) |  | (202,715,000) |
Balance (in shares) at Dec. 31, 2008 |  | 2,046,813 | 2,919,018 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Warrant re-pricing | 44,000 |  |  | 44,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 2,847,000 |  | 1,000 | 2,846,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 571,429 |  |  |  |  |
Issue of common stock upon draw down of Committed Equity Finance Facility | 1,030,000 |  |  | 1,030,000 |  |  |  |
Issue of common stock upon draw down of Committed Equity Finance Facility (in shares) |  |  | 179,289 |  |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock | 7,000 |  |  | 7,000 |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares) |  |  | 7,887 |  |  |  |  |
Stock-based compensation | 810,000 |  |  | 810,000 |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Unrealized foreign exchange on intercompany loans | 5,651,000 |  |  |  | 5,651,000 |  |  | 5,651,000
Translation adjustment | (5,589,000) |  |  |  | (5,589,000) |  |  | (5,589,000)
Loss for the year | (19,570,000) |  |  |  |  |  | (19,570,000) | (19,570,000)
Comprehensive loss | (19,508,000) |  |  |  |  |  |  | (19,508,000)
Balance at Dec. 31, 2009 | 5,872,000 | 2,000 | 4,000 | 228,131,000 | 20,000 |  | (222,285,000) |
Balance (in shares) at Dec. 31, 2009 |  | 2,046,813 | 3,677,623 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 11,897,000 |  | 1,000 | 11,896,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 742,857 |  |  |  |  |
Issue of common stock upon draw down of Committed Equity Finance Facility | 4,863,000 |  |  | 4,863,000 |  |  |  |
Issue of common stock upon draw down of Committed Equity Finance Facility (in shares) |  |  | 402,704 |  |  |  |  |
Warrant exercise | 2,499,000 |  |  | 2,499,000 |  |  |  |
Warrant exercise (in shares) |  |  | 374,038 |  |  |  |  |
Issue of common stock on private placement, net of expenses | 13,980,000 |  | 1,000 | 13,979,000 |  |  |  |
Issue of common stock on private placement, net of expenses (in shares) |  |  | 1,189,028 |  |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock | 77,000 |  |  | 77,000 |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares) |  |  | 29,367 |  |  |  |  |
Preferred stock conversions |  | (1,000) |  | 3,516,000 |  |  | (3,515,000) |
Preferred stock conversions (in shares) |  | (833,671) | 236,514 |  |  |  |  |
Stock-based compensation | 1,746,000 |  |  | 1,746,000 |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Unrealized foreign exchange on intercompany loans | 2,073,000 |  |  |  | (2,073,000) |  |  | (2,073,000)
Translation adjustment | (2,084,000) |  |  |  | 2,084,000 |  |  | 2,084,000
Loss for the year | (16,021,000) |  |  |  |  |  | (16,021,000) | (16,021,000)
Comprehensive loss | (16,010,000) |  |  |  |  |  |  | (16,010,000)
Balance at Dec. 31, 2010 | 24,924,000 | 1,000 | 7,000 | 266,706,000 | 31,000 |  | (241,821,000) |
Balance (in shares) at Dec. 31, 2010 |  | 1,213,142 | 6,652,131 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses | 9,272,000 |  | 1,000 | 9,271,000 |  |  |  |
Issue of common stock for cash on registered direct offering, net of expenses (in shares) |  |  | 1,088,235 |  |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock | 3,000 |  |  | 3,000 |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares) |  |  | 5,414 |  |  |  |  |
Issue of common stock upon exercise of stock options | 3,000 |  |  |  |  |  |  |
Issue of common stock upon exercise of stock options (in shares) | 948 |  |  |  |  |  |  |
Stock-based compensation | 882,000 |  |  | 882,000 |  |  |  |
Preferred stock dividends declared | (364,000) |  |  | (364,000) |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Unrealized foreign exchange on intercompany loans | (622,000) |  |  |  | (622,000) |  |  | (622,000)
Translation adjustment | 648,000 |  |  |  | 648,000 |  |  | 648,000
Loss for the year | (15,243,000) |  |  |  |  |  | (15,243,000) | (15,243,000)
Comprehensive loss | (15,217,000) |  |  |  |  |  |  | (15,217,000)
Balance at Dec. 31, 2011 | 19,500,000 | 1,000 | 8,000 | 276,498,000 | 57,000 |  | (257,064,000) |
Balance (in shares) at Dec. 31, 2011 |  | 1,213,142 | 7,745,780 |  |  |  |  |
Increase (Decrease) in Stockholders' Equity |  |  |  |  |  |  |  |
Issue of common stock on private placement, net of expenses | 1,822,000 |  | 1,000 | 1,821,000 |  |  |  |
Issue of common stock on private placement, net of expenses (in shares) |  |  | 669,726 |  |  |  |  |
Issue of common stock on share purchase agreement | 1,418,000 |  |  | 1,418,000 |  |  |  |
Issue of common stock on share purchase agreement (in shares) |  |  | 233,530 |  |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock | 94,000 |  |  | 94,000 |  |  |  |
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares) |  |  | 37,448 |  |  |  |  |
Issue of common stock upon exercise of stock options | 100,000 |  |  |  |  |  |  |
Issue of common stock upon exercise of stock options (in shares) | 33,351 |  |  |  |  |  |  |
Stock-based compensation | 380,000 |  |  | 380,000 |  |  |  |
Comprehensive loss: |  |  |  |  |  |  |  |
Unrealized foreign exchange on intercompany loans | 4,550,000 |  |  |  | 4,550,000 |  |  | 4,550,000
Translation adjustment | (4,559,000) |  |  |  | (4,559,000) |  |  | (4,559,000)
Loss for the year | (13,186,000) |  |  |  |  |  | (13,186,000) | (13,186,000)
Comprehensive loss | (13,195,000) |  |  |  |  |  |  | (13,195,000)
Balance at Dec. 31, 2012 | $ 10,019,000 | $ 1,000 | $ 9,000 | $ 280,211,000 | $ 48,000 | $ 0 | $ (270,250,000) |
Balance (in shares) at Dec. 31, 2012 |  | 1,213,142 | 8,686,484 |  |  |  |  |

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