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Property, Plant and Equipment (Details) (USD $)
12 Months Ended 197 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Property, plant and equipment        
Property, plant and equipment, gross $ 7,711,000 $ 8,368,000   $ 7,711,000
Less: accumulated depreciation and amortization (7,582,000) (8,201,000)   (7,582,000)
Property, Plant and Equipment, Net 129,000 167,000 167,000 129,000
Depreciation and amortization        
Depreciation and amortization expense 60,000 241,000 457,000 12,615,000
Assets held under capital lease arrangements 0 0   0
Leasehold improvements
       
Property, plant and equipment        
Property, plant and equipment, gross 867,000 844,000   867,000
Leasehold improvements | Minimum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 5 years      
Leasehold improvements | Maximum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 15 years      
Research and laboratory equipment
       
Property, plant and equipment        
Property, plant and equipment, gross 5,519,000 6,251,000   5,519,000
Research and laboratory equipment | Minimum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 3 years      
Research and laboratory equipment | Maximum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 5 years      
Office equipment and furniture
       
Property, plant and equipment        
Property, plant and equipment, gross $ 1,325,000 $ 1,273,000   $ 1,325,000
Office equipment and furniture | Minimum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 3 years      
Office equipment and furniture | Maximum
       
Property, plant and equipment        
Useful lives in years from date of acquisition 5 years