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Taxes (Details 2) (USD $)
 12 Months Ended 197 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Reconciliation of the (benefit) provision for income taxes        
Loss before income taxes $ (15,107,000) $ (15,168,000) $ (15,547,000)  
Income tax expense computed at statutory federal tax rate (5,136,000) (5,157,000) (5,286,000)  
Disallowed expenses and non-taxable income 176,000 (141,000) (490,000)  
Loss surrendered to generate R&D credit 3,025,000 1,372,000 1,605,000  
Additional research and development tax relief (2,656,000) (2,260,000) (793,000)  
Change in valuation allowance (579,000) 2,952,000 3,605,000  
Research and development tax credit rate difference     132,000  
Foreign items, including change in tax rates 3,819,000 2,669,000 570,000  
Current - total (1,351,000) (565,000) (657,000) (19,795,000)
Significant components of the entity's deferred tax assets        
Net operating loss carryforwards 42,399,000 43,870,000   42,399,000
Depreciation, amortization and impairment of property and equipment 1,654,000 1,772,000   1,654,000
Stock Options 1,451,000 1,372,000   1,451,000
Accrued Expenses 3,389,000 3,435,000   3,389,000
Other 45,000 96,000   45,000
Translation adjustment 1,277,000 249,000   1,277,000
Deferred Tax Assets 50,215,000 50,794,000   50,215,000
Valuation allowance for deferred tax assets (50,215,000) (50,794,000)   (50,215,000)
Taxes        
Material uncertain tax positions 0 0   0
Federal
        
Taxes        
NOLs carryforward 19,200,000 18,600,000   19,200,000
Foreign
        
Taxes        
NOLs carryforward 153,400,000 148,200,000   153,400,000
State
        
Taxes        
NOLs carryforward $ 18,300,000     $ 18,300,000