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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $)
Total
Preferred Stock
Common stock
Additional paid-in capital
Accumulated other comprehensive income/(loss)
Deferred compensation
Deficit accumulated during development stage
Comprehensive loss
Balance at Aug. 12, 1996                
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses $ 1,000     $ 1,000        
Comprehensive loss:                
Translation adjustment (4,000)       (4,000)     (4,000)
Loss for the year (290,000)           (290,000) (290,000)
Comprehensive loss (294,000)             (294,000)
Balance at Mar. 31, 1997 (293,000)     1,000 (4,000)   (290,000)  
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 4,217,000     4,217,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     38,111          
Issue of shares for IP rights agreement, research & development agreement and license agreement 262,000     262,000        
Stock-based compensation       2,002,000   (2,002,000)    
Amortization of deferred stock-based compensation 302,000         302,000    
Comprehensive loss:                
Translation adjustment 55,000       55,000     55,000
Loss for the year (2,534,000)           (2,534,000) (2,534,000)
Comprehensive loss (2,479,000)             (2,479,000)
Balance at Mar. 31, 1998 2,009,000     6,482,000 51,000 (1,700,000) (2,824,000)  
Balance (in shares) at Mar. 31, 1998     38,111          
Increase (Decrease) in Stockholders' Equity                
Amortization of deferred stock-based compensation 406,000         406,000    
Comprehensive loss:                
Translation adjustment 11,000       11,000     11,000
Loss for the year (3,964,000)           (3,964,000) (3,964,000)
Comprehensive loss (3,953,000)             (3,953,000)
Balance at Mar. 31, 1999 (1,538,000)     6,482,000 62,000 (1,294,000) (6,788,000)  
Balance (in shares) at Mar. 31, 1999     38,111          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 12,717,000     12,717,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     76,984          
Issue of shares on conversion of bridging loan and Loan Note Instrument 1,638,000     1,638,000        
Issue of shares on conversion of bridging loan and Loan Note Instrument (in shares)     12,943          
Issue of shares in lieu of cash bonus 164,000     164,000        
Issue of shares in lieu of cash bonus (in shares)     1,294          
Issue of shares for IP rights agreement, research & development agreement and license agreement 409,000     409,000        
Issue of common stock upon exercise of stock options 40,000     40,000        
Issue of common stock upon exercise of stock options (in shares)     324          
Stock-based compensation       167,000   (167,000)    
Amortization of deferred stock-based compensation 433,000         433,000    
Comprehensive loss:                
Translation adjustment (194,000)       (194,000)     (194,000)
Loss for the year (5,686,000)           (5,686,000) (5,686,000)
Comprehensive loss (5,880,000)             (5,880,000)
Balance at Mar. 31, 2000 7,983,000     21,617,000 (132,000) (1,028,000) (12,474,000)  
Balance (in shares) at Mar. 31, 2000     129,656          
Increase (Decrease) in Stockholders' Equity                
Stock-based compensation       294,000   (294,000)    
Amortization of deferred stock-based compensation 275,000         275,000    
Comprehensive loss:                
Translation adjustment (466,000)       (466,000)     (466,000)
Loss for the year (10,382,000)           (10,382,000) (10,382,000)
Comprehensive loss (10,848,000)             (10,848,000)
Balance at Mar. 31, 2001 (2,590,000)     21,911,000 (598,000) (1,047,000) (22,856,000)  
Balance (in shares) at Mar. 31, 2001     129,656          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     779          
Issue of warrants in connection with registered direct offering 1,215,000     1,215,000        
Issue of shares for IP rights agreement, research & development agreement and license agreement 183,000     183,000        
Issue of shares for IP rights agreement, research & development agreement and license agreement (in shares)     644          
Issue of common stock upon exercise of stock options 106,000     106,000        
Stock-based compensation       363,000   (363,000)    
Amortization of deferred stock-based compensation 672,000         672,000    
Comprehensive loss:                
Translation adjustment 191,000       191,000     191,000
Loss for the year (14,853,000)           (14,853,000) (14,853,000)
Comprehensive loss (14,662,000)             (14,662,000)
Balance at Mar. 31, 2002 (15,076,000)     23,778,000 (407,000) (738,000) (37,709,000)  
Balance (in shares) at Mar. 31, 2002     131,079          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock upon exercise of stock options 12,000     12,000        
Stock-based compensation       (84,000)   84,000    
Amortization of deferred stock-based compensation 305,000         305,000    
Comprehensive loss:                
Translation adjustment (1,846,000)       (1,846,000)     (1,846,000)
Loss for the year (15,542,000)           (15,542,000) (15,542,000)
Comprehensive loss (17,388,000)             (17,388,000)
Balance at Mar. 31, 2003 (32,147,000)     23,706,000 (2,253,000) (349,000) (53,251,000)  
Balance (in shares) at Mar. 31, 2003     131,079          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 27,635,000     27,635,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     215,755          
Preferred stock conversions 58,148,000   1,000 58,147,000        
Preferred stock conversions (in shares)     538,449          
Issue of common stock upon exercise of stock options 115,000     115,000        
Issue of common stock upon exercise of stock options (in shares)     936          
Amortization of deferred stock-based compensation 217,000         217,000    
Comprehensive loss:                
Translation adjustment (1,343,000)       (1,343,000)     (1,343,000)
Loss for the year (14,977,000)           (14,977,000) (14,977,000)
Comprehensive loss (16,320,000)             (16,320,000)
Balance at Dec. 31, 2003 37,648,000   1,000 109,603,000 (3,596,000) (132,000) (68,228,000)  
Balance (in shares) at Dec. 31, 2003     886,219          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 8,541,000     8,541,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     61,510          
Warrant exercise (in shares)     3,233          
Stock-based compensation (1,918,000)     (2,050,000)   132,000    
Comprehensive loss:                
Translation adjustment 2,424,000       2,424,000     2,424,000
Loss for the year (22,742,000)           (22,742,000) (22,742,000)
Comprehensive loss (20,318,000)             (20,318,000)
Balance at Dec. 31, 2004 23,953,000   1,000 116,094,000 (1,172,000)   (90,970,000)  
Balance (in shares) at Dec. 31, 2004     950,962          
Comprehensive loss:                
Translation adjustment (1,786,000)       (1,786,000)     (1,786,000)
Loss for the year (18,048,000)           (18,048,000) (18,048,000)
Comprehensive loss (19,834,000)             (19,834,000)
Balance at Dec. 31, 2005 4,119,000   1,000 116,094,000 (2,958,000)   (109,018,000)  
Balance (in shares) at Dec. 31, 2005     950,962          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares)     92,630          
Issue of shares on conversion of bridging loan and Loan Note Instrument (in shares)     65,187          
Reverse Acquisition 16,255,000 2,000   16,253,000        
Reverse Acquisition (in shares)   2,046,813 281,133          
Loan from Cyclacel Group plc waived 10,420,000     10,420,000        
Issue of common stock and warrants for cash 42,362,000   1,000 42,361,000        
Issue of common stock and warrants for cash (in shares)     918,367          
Stock-based compensation 9,600,000     9,600,000        
Change in unrealized loss on investment 5,000       5,000      
Comprehensive loss:                
Translation adjustment 416,000       416,000     416,000
Loss for the year (29,258,000)           (29,258,000) (29,258,000)
Comprehensive loss (28,842,000)             (28,842,000)
Balance at Dec. 31, 2006 53,919,000 2,000 2,000 194,728,000 (2,537,000)   (138,276,000)  
Balance (in shares) at Dec. 31, 2006   2,046,813 2,308,279          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 33,357,000   1,000 33,356,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     607,095          
Issue of warrants in connection with registered direct offering (6,750,000)     (6,750,000)        
Issue of common stock upon exercise of stock options 163,000     163,000        
Issue of common stock upon exercise of stock options (in shares)     3,644          
Stock-based compensation 1,733,000     1,733,000        
Preferred stock dividends declared (307,000)     (307,000)        
Comprehensive loss:                
Translation adjustment (93,000)       (93,000)     (93,000)
Loss for the year (24,053,000)           (24,053,000) (24,053,000)
Comprehensive loss (24,146,000)             (24,146,000)
Balance at Dec. 31, 2007 57,969,000 2,000 3,000 222,923,000 (2,630,000)   (162,329,000)  
Balance (in shares) at Dec. 31, 2007   2,046,813 2,919,018          
Increase (Decrease) in Stockholders' Equity                
Stock-based compensation 1,698,000     1,698,000        
Preferred stock dividends declared (1,227,000)     (1,227,000)        
Comprehensive loss:                
Unrealized foreign exchange on intercompany loans (12,330,000)       (12,330,000)     (12,330,000)
Translation adjustment 14,918,000       14,918,000     14,918,000
Loss for the year (40,386,000)           (40,386,000) (40,386,000)
Comprehensive loss (37,798,000)             (37,798,000)
Balance at Dec. 31, 2008 20,642,000 2,000 3,000 223,394,000 (42,000)   (202,715,000)  
Balance (in shares) at Dec. 31, 2008   2,046,813 2,919,018          
Increase (Decrease) in Stockholders' Equity                
Warrant re-pricing 44,000     44,000        
Issue of common stock for cash on registered direct offering, net of expenses 2,847,000   1,000 2,846,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     571,429          
Issue of common stock upon draw down of Committed Equity Finance Facility 1,030,000     1,030,000        
Issue of common stock upon draw down of Committed Equity Finance Facility (in shares)     179,289          
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock 7,000     7,000        
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares)     7,887          
Stock-based compensation 810,000     810,000        
Comprehensive loss:                
Unrealized foreign exchange on intercompany loans 5,651,000       5,651,000     5,651,000
Translation adjustment (5,589,000)       (5,589,000)     (5,589,000)
Loss for the year (19,570,000)           (19,570,000) (19,570,000)
Comprehensive loss (19,508,000)             (19,508,000)
Balance at Dec. 31, 2009 5,872,000 2,000 4,000 228,131,000 20,000   (222,285,000)  
Balance (in shares) at Dec. 31, 2009   2,046,813 3,677,623          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 11,897,000   1,000 11,896,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     742,857          
Issue of common stock upon draw down of Committed Equity Finance Facility 4,863,000     4,863,000        
Issue of common stock upon draw down of Committed Equity Finance Facility (in shares)     402,704          
Warrant exercise 2,499,000     2,499,000        
Warrant exercise (in shares)     374,038          
Issue of common stock on private placement, net of expenses 13,980,000   1,000 13,979,000        
Issue of common stock on private placement, net of expenses (in shares)     1,189,028          
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock 77,000     77,000        
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares)     29,367          
Preferred stock conversions   (1,000)   3,516,000     (3,515,000)  
Preferred stock conversions (in shares)   (833,671) 236,514          
Stock-based compensation 1,746,000     1,746,000        
Comprehensive loss:                
Unrealized foreign exchange on intercompany loans 2,073,000       (2,073,000)     (2,073,000)
Translation adjustment (2,084,000)       2,084,000     2,084,000
Loss for the year (16,021,000)           (16,021,000) (16,021,000)
Comprehensive loss (16,010,000)             (16,010,000)
Balance at Dec. 31, 2010 24,924,000 1,000 7,000 266,706,000 31,000   (241,821,000)  
Balance (in shares) at Dec. 31, 2010   1,213,142 6,652,131          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock for cash on registered direct offering, net of expenses 9,272,000   1,000 9,271,000        
Issue of common stock for cash on registered direct offering, net of expenses (in shares)     1,088,235          
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock 3,000     3,000        
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares)     5,414          
Issue of common stock upon exercise of stock options 3,000              
Issue of common stock upon exercise of stock options (in shares) 948              
Stock-based compensation 882,000     882,000        
Preferred stock dividends declared (364,000)     (364,000)        
Comprehensive loss:                
Unrealized foreign exchange on intercompany loans (622,000)       (622,000)     (622,000)
Translation adjustment 648,000       648,000     648,000
Loss for the year (15,243,000)           (15,243,000) (15,243,000)
Comprehensive loss (15,217,000)             (15,217,000)
Balance at Dec. 31, 2011 19,500,000 1,000 8,000 276,498,000 57,000   (257,064,000)  
Balance (in shares) at Dec. 31, 2011   1,213,142 7,745,780          
Increase (Decrease) in Stockholders' Equity                
Issue of common stock on private placement, net of expenses 1,822,000   1,000 1,821,000        
Issue of common stock on private placement, net of expenses (in shares)     669,726          
Issue of common stock on share purchase agreement 1,418,000     1,418,000        
Issue of common stock on share purchase agreement (in shares)     233,530          
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock 94,000     94,000        
Issue of common stock to certain directors and officers upon exercise of stock options, stock-based awards exercised,restricted stock units and restricted stock (in shares)     37,448          
Issue of common stock upon exercise of stock options 100,000              
Issue of common stock upon exercise of stock options (in shares) 33,351              
Stock-based compensation 380,000     380,000        
Comprehensive loss:                
Unrealized foreign exchange on intercompany loans 4,550,000       4,550,000     4,550,000
Translation adjustment (4,559,000)       (4,559,000)     (4,559,000)
Loss for the year (13,186,000)           (13,186,000) (13,186,000)
Comprehensive loss (13,195,000)             (13,195,000)
Balance at Dec. 31, 2012 $ 10,019,000 $ 1,000 $ 9,000 $ 280,211,000 $ 48,000 $ 0 $ (270,250,000)  
Balance (in shares) at Dec. 31, 2012   1,213,142 8,686,484