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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 200 Months Ended
Mar. 31, 2013
Mar. 31, 2012
Mar. 31, 2013
Revenues:      
Collaboration and research and development revenue     $ 3,100
Grant revenue 212   3,929
Total revenues 212   7,029
Operating expenses:      
Research and development 1,580 1,347 193,971
General and administrative 2,683 1,768 92,094
Goodwill and intangibles impairment     2,747
Other restructuring costs     2,634
Total operating expenses 4,263 3,115 291,446
Operating loss (4,051) (3,115) (284,417)
Other income (expense):      
Costs associated with aborted 2004 IPO     (3,550)
Payment under guarantee     (1,652)
Non-cash consideration associated with stock purchase agreement     (423)
Change in valuation of Economic Rights 570 (56) 547
Change in valuation of liabilities measured at fair value   42 6,378
Foreign exchange losses 120 114 (3,885)
Interest income 1 6 13,748
Interest expense     (4,567)
Other income (expense) 4 47 81
Total other (expense) income, net 695 153 6,677
Loss from continuing operations before taxes (3,356) (2,962) (277,740)
Income tax benefit 258 168 20,053
Net loss from continuing operations (3,098) (2,794) (257,687)
Discontinued operations:      
(Loss) income from discontinued operations, net of tax of $0 and $10 for the three months ended March 31, 2012 and 2013, respectively 16 (161) (12,130)
Net loss (3,082) (2,955) (269,817)
Dividend on preferred ordinary shares     (38,123)
Deemed dividend on convertible exchangeable preferred shares (8,366)   (11,881)
Dividend on convertible exchangeable preferred shares (122) (182) (4,507)
Net loss applicable to common shareholders $ (11,570) $ (3,137) $ (324,328)
Net loss per share, continuing operations - basic and diluted (in dollars per share) $ (1.18) $ (0.38)  
Net loss per share, discontinued operations - basic and diluted (in dollars per share)   $ (0.02)  
Net loss per share - basic and diluted (in dollars per share) $ (1.18) $ (0.40)  
Weighted average common shares outstanding (in shares) 9,790,474 7,823,089