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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 6 Months Ended 203 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Revenues:          
Collaboration and research and development revenue         $ 3,100
Grant revenue 264 26 476 26 4,193
Total revenues 264 26 476 26 7,293
Operating expenses:          
Research and development 2,631 1,717 4,211 3,064 196,602
General and administrative 1,787 2,121 4,470 3,889 93,881
Goodwill and intangibles impairment         2,747
Other restructuring costs         2,634
Total operating expenses 4,418 3,838 8,681 6,953 295,864
Operating loss (4,154) (3,812) (8,205) (6,927) (288,571)
Other income (expense):          
Costs associated with aborted 2004 IPO         (3,550)
Payment under guarantee         (1,652)
Non-cash consideration associated with stock purchase agreement         (423)
Change in valuation of Economic Rights   146 570 90 547
Change in valuation of liabilities measured at fair value   8   50 6,378
Foreign exchange gains (losses) (101) 117 19 231 (3,986)
Interest income 3 6 4 12 13,751
Interest expense         (4,567)
Other income (expense), net 5,500 29 5,504 76 5,581
Total other income 5,402 306 6,097 459 12,079
(Loss) income from continuing operations before taxes 1,248 (3,506) (2,108) (6,468) (276,492)
Income tax benefit, net 230 127 488 295 20,283
Net (loss) income from continuing operations 1,478 (3,379) (1,620) (6,173) (256,209)
Discontinued operations:          
(Loss) income from discontinued operations 24 (198) 50 (359) (11,759)
Income tax on discontinued operations (10)   (20)   (357)
Net (loss) income from discontinued operations 14 (198) 30 (359) (12,116)
Net (loss) income 1,492 (3,577) (1,590) (6,532) (268,325)
Dividend on preferred ordinary shares         (38,123)
Deemed dividend on convertible exchangeable preferred shares     (8,366)   (11,881)
Dividend on convertible exchangeable preferred shares (63) (182) (185) (364) (4,570)
Net (loss) income applicable to common shareholders $ 1,429 $ (3,759) $ (10,141) $ (6,896) $ (322,899)
Basic earnings per common share:          
Net (loss) income per share, continuing operations (in dollars per share) $ 0.10 $ (0.42) $ (0.86) $ (0.80)  
Net (loss) income per share, discontinued operations (in dollars per share) $ 0.00 $ (0.02) $ 0.00 $ (0.04)  
Net (loss) income applicable to common shareholders (in dollars per share) $ 0.10 $ (0.45) $ (0.86) $ (0.85)  
Diluted earnings per common share:          
Net (loss) income per share, continuing operations (in dollars per share) $ 0.10 $ (0.42) $ (0.86) $ (0.80)  
Net (loss) income per share, discontinued operations (in dollars per share) $ 0.00 $ (0.02) $ 0.00 $ (0.04)  
Net (loss) income applicable to common shareholders (in dollars per share) $ 0.10 $ (0.45) $ (0.86) $ (0.85)  
Weighted average shares of common stock outstanding:          
Basic (in shares) 13,885,442 8,428,154 11,849,270 8,125,621  
Diluted (in shares) 13,927,371 8,428,154 11,849,270 8,125,621