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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 9 Months Ended 206 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Revenues:          
Collaboration and research and development revenue         $ 3,100
Grant revenue 309 38 785 64 4,502
Total revenues 309 38 785 64 7,602
Operating expenses:          
Research and development 4,575 1,532 8,786 4,596 201,177
General and administrative 1,529 2,028 5,999 5,917 95,410
Goodwill and intangibles impairment         2,747
Other restructuring costs         2,634
Total operating expenses 6,104 3,560 14,785 10,513 301,968
Operating loss (5,795) (3,522) (14,000) (10,449) (294,366)
Other income (expense):          
Costs associated with aborted 2004 IPO         (3,550)
Payment under guarantee         (1,652)
Non-cash consideration associated with stock purchase agreement         (423)
Change in valuation of Economic Rights   (63) 570 27 547
Change in valuation of liabilities measured at fair value   1   51 6,378
Foreign exchange gain (loss) 25 6 44 237 (3,961)
Interest income 8 5 12 17 13,759
Interest expense         (4,567)
Other income (expense), net 16 1 5,520 77 5,597
Total other (expense) income 49 (50) 6,146 409 12,128
Loss from continuing operations before taxes (5,746) (3,572) (7,854) (10,040) (282,238)
Income tax benefit 730 419 1,218 714 21,013
Net loss from continuing operations (5,016) (3,153) (6,636) (9,326) (261,225)
Discontinued operations:          
Income (loss) from discontinued operations 20 1,263 70 904 (11,739)
Income tax on discontinued operations (8)   (28)   (365)
Net income (loss) from discontinued operations 12 1,263 42 904 (12,104)
Net loss (5,004) (1,890) (6,594) (8,422) (273,329)
Dividend on preferred ordinary shares         (38,123)
Deemed dividend on convertible exchangeable preferred shares (661)   (9,027)   (12,542)
Dividend on convertible exchangeable preferred shares (63) (182) (248) (546) (4,633)
Net loss applicable to common shareholders $ (5,728) $ (2,072) $ (15,869) $ (8,968) $ (328,627)
Net loss per share, continuing operations - Basic and diluted (in dollars per share) $ (0.32) $ (0.40) $ (1.15) $ (1.20)  
Net income per share, discontinued operations - Basic and diluted (in dollars per share) $ 0.00 $ 0.15 $ 0.00 $ 0.11  
Net loss applicable to common shareholders - Basic and diluted (in dollars per share) $ (0.32) $ (0.25) $ (1.15) $ (1.09)  
Weighted average common shares outstanding (in shares) 17,788,568 8,429,269 13,850,792 8,227,721