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Taxes (Details 2) (USD $) | 3 Months Ended | 9 Months Ended | 12 Months Ended | 185 Months Ended | 194 Months Ended
--- | --- | --- | --- | --- | ---
Sep. 30, 2012 | Sep. 30, 2011 | Sep. 30, 2012 | Sep. 30, 2011 | Dec. 31, 2011 | Dec. 31, 2010 | Dec. 31, 2009 | Dec. 31, 2011 | Sep. 30, 2012
Reconciliation of the (benefit) provision for income taxes |  |  |  |  |  |  |  |  |
Loss before taxes |  |  |  |  | $ (15,808,000) | $ (16,678,000) | $ (20,518,000) |  |
Income tax expense computed at statutory federal tax rate |  |  |  |  | (5,375,000) | (5,672,000) | (6,976,000) |  |
State income tax (net of federal benefit) |  |  |  |  |  | 7,000 | 8,000 |  |
Disallowed expenses and non-taxable income |  |  |  |  | (141,000) | (490,000) | (773,000) |  |
Loss surrendered to generate R&D credit |  |  |  |  | 1,372,000 | 1,605,000 | 2,322,000 |  |
Additional research and development tax relief |  |  |  |  | (2,260,000) | (793,000) | (1,185,000) |  |
Change in valuation allowance |  |  |  |  | 3,170,000 | 3,984,000 | 4,605,000 |  |
Research and development tax credit rate difference |  |  |  |  |  | 132,000 | 237,000 |  |
Foreign items, including change in tax rates |  |  |  |  | 2,669,000 | 570,000 | 814,000 |  |
Current - total | (419,000) | (126,000) | (714,000) | (443,000) | (565,000) | (657,000) | (948,000) | (18,444,000) | (19,158,000)
Significant components of the entity's deferred tax assets |  |  |  |  |  |  |  |  |
Net operating loss carryforwards |  |  |  |  | 43,870,000 | 43,056,000 |  | 43,870,000 |
Depreciation, amortization and impairment of property and equipment |  |  |  |  | 1,772,000 | 1,925,000 |  | 1,772,000 |
Stock Options |  |  |  |  | 1,372,000 | 1,228,000 |  | 1,372,000 |
Accrued Expenses |  |  |  |  | 3,435,000 | 3,778,000 |  | 3,435,000 |
Other |  |  |  |  | 96,000 | 89,000 |  | 96,000 |
Translation adjustment |  |  |  |  | 249,000 | (2,452,000) |  | 249,000 |
Deferred Tax Assets |  |  |  |  | 50,794,000 | 47,624,000 |  | 50,794,000 |
Valuation allowance for deferred tax assets |  |  |  |  | (50,794,000) | (47,624,000) |  | (50,794,000) |
Net deferred taxes |  |  |  |  | 0 | 0 |  | 0 |
Accumulated tax losses |  |  |  |  | 148,274,000 | 132,521,000 |  | 148,274,000 |
Federal and foreign |  |  |  |  |  |  |  |  |
Taxes |  |  |  |  |  |  |  |  |
NOLs carryforward |  |  |  |  | $ 166,900,000 | $ 147,700,000 |  | $ 166,900,000 |

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- Definition The sum of domestic, foreign and state and local operating loss carryforwards, before tax effects, available to reduce future taxable income under enacted tax laws. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 3 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=6907707&loc=d3e32559-109319 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 109 -Paragraph 48 -Subparagraph a -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. + Details
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