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Property, Plant and Equipment (Details) (USD $) | 9 Months Ended | 12 Months Ended | 185 Months Ended | 194 Months Ended
--- | --- | --- | --- | ---
Sep. 30, 2012 | Sep. 30, 2011 | Dec. 31, 2011 | Dec. 31, 2010 | Dec. 31, 2009 | Dec. 31, 2011 | Sep. 30, 2012
Property, plant and equipment |  |  |  |  |  |  |
Property, plant and equipment, gross |  |  | $ 8,368,000 | $ 8,392,000 |  | $ 8,368,000 |
Less: accumulated depreciation and amortization |  |  | (8,201,000) | (7,984,000) |  | (8,201,000) |
Property, Plant and Equipment, Net | 140,000 |  | 167,000 | 408,000 |  | 167,000 | 140,000
Depreciation and amortization |  |  |  |  |  |  |
Depreciation and amortization expense | 45,000 | 250,000 | 241,000 | 457,000 | 668,000 | 12,555,000 | 12,600,000
Asset impairment charges recorded as accelerated depreciation |  |  |  |  | 200,000 |  |
Leasehold improvements |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Property, plant and equipment, gross |  |  | 844,000 | 844,000 |  | 844,000 |
Leasehold improvements | Minimum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 5 years |  |  |  |
Leasehold improvements | Maximum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 15 years |  |  |  |
Research and laboratory equipment |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Property, plant and equipment, gross |  |  | 6,251,000 | 6,281,000 |  | 6,251,000 |
Research and laboratory equipment | Minimum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 3 years |  |  |  |
Research and laboratory equipment | Maximum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 5 years |  |  |  |
Office equipment and furniture |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Property, plant and equipment, gross |  |  | $ 1,273,000 | $ 1,267,000 |  | $ 1,273,000 |
Office equipment and furniture | Minimum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 3 years |  |  |  |
Office equipment and furniture | Maximum |  |  |  |  |  |  |
Property, plant and equipment |  |  |  |  |  |  |
Useful lives in years from date of acquisition |  |  | 5 years |  |  |  |

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- Definition The cumulative amount of depreciation, depletion and amortization (related to property, plant and equipment, but not including land) that has been recognized in the income statement. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 14 -Article 5 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Principles Board Opinion (APB) -Number 12 -Paragraph 5 -Subparagraph c -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Principles Board Opinion (APB) -Number 12 -Paragraph 5 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.14) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 + Details
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- Definition The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6943989&loc=d3e3602-108585 + Details
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- Definition Gross amount of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher AICPA -Name Accounting Principles Board Opinion (APB) -Number 12 -Paragraph 5 -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.13) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 + Details
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- Definition Amount, net of accumulated depreciation, depletion and amortization, of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 03 -Paragraph 8 -Article 7 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Statement of Financial Accounting Standard (FAS) -Number 12 -Paragraph 5 -Subparagraph b, c -LegacyDoc This reference is SUPERSEDED by the Accounting Standards Codification effective for interim and annual periods ending after September 15, 2009. This reference is included to help users transition from the previous accounting hierarchy and will be removed from future versions of this taxonomy. Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6391035&loc=d3e2868-110229 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.13) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 13 -Subparagraph a -Article 5 + Details
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- Definition Useful life of long lived, physical assets used in the normal conduct of business and not intended for resale, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. Examples include, but not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment. + References No definition available. + Details
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