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Property, Plant and Equipment (Details) (USD $)
9 Months Ended 12 Months Ended 185 Months Ended 194 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 31, 2011
Sep. 30, 2012
Property, plant and equipment              
Property, plant and equipment, gross     $ 8,368,000 $ 8,392,000   $ 8,368,000  
Less: accumulated depreciation and amortization     (8,201,000) (7,984,000)   (8,201,000)  
Property, Plant and Equipment, Net 140,000   167,000 408,000   167,000 140,000
Depreciation and amortization              
Depreciation and amortization expense 45,000 250,000 241,000 457,000 668,000 12,555,000 12,600,000
Asset impairment charges recorded as accelerated depreciation         200,000    
Leasehold improvements
             
Property, plant and equipment              
Property, plant and equipment, gross     844,000 844,000   844,000  
Leasehold improvements | Minimum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     5 years        
Leasehold improvements | Maximum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     15 years        
Research and laboratory equipment
             
Property, plant and equipment              
Property, plant and equipment, gross     6,251,000 6,281,000   6,251,000  
Research and laboratory equipment | Minimum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     3 years        
Research and laboratory equipment | Maximum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     5 years        
Office equipment and furniture
             
Property, plant and equipment              
Property, plant and equipment, gross     $ 1,273,000 $ 1,267,000   $ 1,273,000  
Office equipment and furniture | Minimum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     3 years        
Office equipment and furniture | Maximum
             
Property, plant and equipment              
Useful lives in years from date of acquisition     5 years