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Restructuring (Details) (USD $)
 12 Months Ended 185 Months Ended 194 Months Ended
Dec. 31, 2010
Dec. 31, 2009
item
Dec. 31, 2011
Sep. 30, 2012
Restructuring        
Number of positions by which the workforce was reduced   51    
Accelerated depreciation   $ 200,000    
Surrender fee due to termination of lease   366,000 2,634,000 2,634,000
Reconciliation of provisions        
Balance at the beginning of the period 1,062,000      
Cash payments (1,104,000)      
Adjustments for lease-related deferred expenses and liabilities 42,000      
Balance at the end of the period 0 1,062,000    
Employee severance
        
Restructuring        
Severance payments   400,000    
Lease restructuring charges
        
Restructuring        
Accelerated depreciation   200,000    
Surrender fee due to termination of lease   100,000    
Reconciliation of provisions        
Balance at the beginning of the period 1,062,000      
Cash payments (1,104,000)      
Adjustments for lease-related deferred expenses and liabilities 42,000      
Balance at the end of the period $ 0 $ 1,062,000