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Taxes (Details 2) (USD $)
 3 Months Ended 9 Months Ended 12 Months Ended 185 Months Ended 194 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Dec. 31, 2011
Sep. 30, 2012
Reconciliation of the (benefit) provision for income taxes                  
Loss before taxes         $ (15,808,000) $ (16,678,000) $ (20,518,000)    
Income tax expense computed at statutory federal tax rate         (5,375,000) (5,672,000) (6,976,000)    
State income tax (net of federal benefit)           7,000 8,000    
Disallowed expenses and non-taxable income         (141,000) (490,000) (773,000)    
Loss surrendered to generate R&D credit         1,372,000 1,605,000 2,322,000    
Additional research and development tax relief         (2,260,000) (793,000) (1,185,000)    
Change in valuation allowance         3,170,000 3,984,000 4,605,000    
Research and development tax credit rate difference           132,000 237,000    
Foreign items, including change in tax rates         2,669,000 570,000 814,000    
Current - total (419,000) (126,000) (714,000) (443,000) (565,000) (657,000) (948,000) (18,444,000) (19,158,000)
Significant components of the entity's deferred tax assets                  
Net operating loss carryforwards         43,870,000 43,056,000   43,870,000  
Depreciation, amortization and impairment of property and equipment         1,772,000 1,925,000   1,772,000  
Stock Options         1,372,000 1,228,000   1,372,000  
Accrued Expenses         3,435,000 3,778,000   3,435,000  
Other         96,000 89,000   96,000  
Translation adjustment         249,000 (2,452,000)   249,000  
Deferred Tax Assets         50,794,000 47,624,000   50,794,000  
Valuation allowance for deferred tax assets         (50,794,000) (47,624,000)   (50,794,000)  
Net deferred taxes         0 0   0  
Accumulated tax losses         148,274,000 132,521,000   148,274,000  
Federal and foreign
                  
Taxes                  
NOLs carryforward         $ 166,900,000 $ 147,700,000   $ 166,900,000