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Fair Value (Details 3) (USD $)	12 Months Ended		209 Months Ended	11 Months Ended	12 Months Ended	1 Months Ended	0 Months Ended	12 Months Ended			1 Months Ended	12 Months Ended		1 Months Ended	12 Months Ended
	Dec. 31, 2013	Dec. 31, 2012	Dec. 31, 2013	Nov. 14, 2013 Purchase Agreement Aspire Capital Fund, LLC	Dec. 31, 2013 Purchase Agreement Aspire Capital Fund, LLC	Apr. 30, 2013 Definitive Agreement Celgene Corporation	Mar. 22, 2012 Economic Rights	Dec. 31, 2013 Economic Rights	Dec. 31, 2012 Economic Rights Minimum	Dec. 31, 2012 Economic Rights Maximum	Apr. 30, 2013 Economic Rights Definitive Agreement	Dec. 31, 2013 Economic Rights Definitive Agreement	Dec. 31, 2012 Economic Rights Definitive Agreement	Feb. 28, 2007 Warrants	Dec. 31, 2012 Warrants	Dec. 31, 2011 Warrants
Fair value measurements
Number of shares issued under purchase agreement				511,509
Purchase price for shares issued under purchase agreement	$ 9,126,000	$ 1,418,000		$ 2,000,000
Shares committed to purchase				3,042,038
Period of common stock purchase agreement				2 years
Fair value of financial instrument				500,000	400,000
Decrease in the fair value of the Purchase Agreement					(100,000)
Amount to be paid as percentage of future litigation settlement amount received							10.00%
One-time payment received for patent related uses						5,500,000
Payment made to economic right holder											600,000
Fair value of the liability													1,100,000
Change in valuation of Economic Rights	570,000	(23,000)	547,000									(600,000)
Warrants Liability
Fair value of the warrants														6,800,000	0
Risk free interest rate (as a percent)														4.68%
Expected volatility (as a percent)									25.00%	75.00%				85.00%
Expected dividend yield (as a percent)														0.00%
Contractual life														7 years
Expected term															1 month 17 days
Change in fair value of warrants								$ 570,000							$ 100,000	$ 600,000

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Amount of increase (decrease) in the fair value of derivatives recognized in the income statement.

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Expected dividends to be paid to holders of the underlying shares or financial instruments (expressed as a percentage of the share or instrument's price).

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