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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 212 Months Ended
Mar. 31, 2014
Mar. 31, 2013
Mar. 31, 2014
Revenues:      
Collaboration and research and development revenue     $ 3,100
Grant revenue 396 212 5,197
Total revenues 396 212 8,297
Operating expenses:      
Research and development 4,344 1,580 208,012
General and administrative 1,462 2,683 98,654
Goodwill and intangibles impairment     2,747
Other restructuring costs     2,634
Total operating expenses 5,806 4,263 312,047
Operating loss (5,410) (4,051) (303,750)
Other income (expense):      
Costs associated with aborted 2004 IPO     (3,550)
Payment under guarantee     (1,652)
Change in valuation of financial instruments associated with stock purchase agreement (47)   (568)
Change in valuation of Economic Rights   570 547
Change in valuation of liabilities measured at fair value     6,378
Foreign exchange gains (losses) 10 120 (3,933)
Interest income 1 1 13,761
Interest expense     (4,567)
Other income, net   4 5,624
Total other income (expense) (36) 695 12,040
Loss from continuing operations before taxes (5,446) (3,356) (291,710)
Income tax benefit 569 258 22,034
Net loss from continuing operations (4,877) (3,098) (269,676)
Discontinued operations:      
Income (loss) from discontinued operations 13 26 (11,705)
Income tax on discontinued operations (5) (10) (376)
Net income (loss) from discontinued operations 8 16 (12,081)
Net loss (4,869) (3,082) (281,757)
Dividend on preferred ordinary shares     (38,123)
Deemed dividend on convertible exchangeable preferred shares   (8,366) (12,542)
Dividend on convertible exchangeable preferred shares (50) (122) (4,733)
Net loss applicable to common shareholders $ (4,919) $ (11,570) $ (337,155)
Net loss per share, continuing operations - Basic and diluted (in dollars per share) $ (0.25) $ (1.18)  
Net loss per share, discontinued operations - Basic and diluted (in dollars per share) $ 0.00 $ 0.00  
Net loss applicable to common shareholders - Basic and diluted (in dollars per share) $ (0.25) $ (1.18)  
Weighted average shares of common stock outstanding (in shares) 19,530,322 9,790,474