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CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) (USD $) In Thousands, unless otherwise specified | 3 Months Ended
--- | ---
Mar. 31, 2015 | Mar. 31, 2014
Operating activities: |  |
Net loss | $ (4,912)us-gaap_NetIncomeLoss | $ (4,869)us-gaap_NetIncomeLoss
Change in valuation of financial instruments associated with stock purchase agreement | 20 cycc_ExpenseRelatedToStockPurchaseAgreement | 47 cycc_ExpenseRelatedToStockPurchaseAgreement
Depreciation | 52 us-gaap_DepreciationDepletionAndAmortization | 23 us-gaap_DepreciationDepletionAndAmortization
Stock-based compensation | 164 us-gaap_ShareBasedCompensation | 187 us-gaap_ShareBasedCompensation
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | (1,111)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets | (1,360)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Accounts payable and other current liabilities | 887 us-gaap_IncreaseDecreaseInAccountsPayableAndOtherOperatingLiabilities | 1,246 us-gaap_IncreaseDecreaseInAccountsPayableAndOtherOperatingLiabilities
Net cash used in operating activities | (4,900)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (4,726)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Investing activities: |  |
Purchase of property, plant and equipment | (14)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment | (31)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Minimum royalty payments received from termination of ALIGN license agreement | 23 us-gaap_PaymentsForProceedsFromOtherInvestingActivities | 96 us-gaap_PaymentsForProceedsFromOtherInvestingActivities
Net cash provided by investing activities | 9 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations | 65 us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Financing activities: |  |
Proceeds from issuance of common stock, net of issuance costs | 10,433 us-gaap_ProceedsFromIssuanceOfCommonStock | 1,676 us-gaap_ProceedsFromIssuanceOfCommonStock
Payment of preferred stock dividend | (50)us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock | (50)us-gaap_PaymentsOfDividendsPreferredStockAndPreferenceStock
Net cash provided by financing activities | 10,383 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations | 1,626 us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Effect of exchange rate changes on cash and cash equivalents | (318)us-gaap_EffectOfExchangeRateOnCashAndCashEquivalentsContinuingOperations | 43 us-gaap_EffectOfExchangeRateOnCashAndCashEquivalentsContinuingOperations
Net (decrease) increase in cash and cash equivalents | 5,174 us-gaap_NetCashProvidedByUsedInContinuingOperations | (2,992)us-gaap_NetCashProvidedByUsedInContinuingOperations
Cash and cash equivalents, beginning of period | 24,189 us-gaap_CashAndCashEquivalentsAtCarryingValue | 31,146 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents, end of period | 29,363 us-gaap_CashAndCashEquivalentsAtCarryingValue | 28,154 us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash received during the period for: |  |
Interest | 1 us-gaap_ProceedsFromInterestReceived | 1 us-gaap_ProceedsFromInterestReceived
Cash paid during the period for: |  |
Taxes |  | $ 25 us-gaap_IncomeTaxesPaid

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- Definition Amount of cash inflow (outflow) of financing activities, excluding discontinued operations. Financing activity cash flows include obtaining resources from owners and providing them with a return on, and a return of, their investment; borrowing money and repaying amounts borrowed, or settling the obligation; and obtaining and paying for other resources obtained from creditors on long-term credit. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3574-108585 + Details
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- Definition Amount of cash inflow (outflow) of investing activities, excluding discontinued operations. Investing activity cash flows include making and collecting loans and acquiring and disposing of debt or equity instruments and property, plant, and equipment and other productive assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 26 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3574-108585 + Details
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- Definition Amount of cash inflow (outflow) from operating activities, excluding discontinued operations. Operating activity cash flows include transactions, adjustments, and changes in value not defined as investing or financing activities. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 25 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3536-108585 + Details
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