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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2015 | Dec. 31, 2014
Revenues: |  |
Grant revenue | $ 1,694 | $ 1,734
Collaboration and research and development revenue | 250 |
Total revenues | 1,944 | 1,734
Operating expenses: |  |
Research and development | 12,382 | 18,277
General and administrative | 5,732 | 5,894
Total operating expenses | 18,114 | 24,171
Operating loss | (16,170) | (22,437)
Other income (expense): |  |
Change in valuation of financial instruments associated with stock purchase agreement | (51) | (342)
Change in valuation of liabilities measured at fair value |  | 20
Foreign exchange gains | (368) | (10)
Interest income | 9 | 6
Other income, net | 94 | 114
Total other income (expense), net | (316) | (212)
Loss from continuing operations before taxes | (16,486) | (22,649)
Income tax benefit | 2,144 | 3,243
Net loss from continuing operations | (14,342) | (19,406)
Discontinued operations: |  |
Income from discontinued operations |  | 29
Income tax on discontinued operations |  | (10)
Net income from discontinued operations |  | 19
Net loss | $ (14,342) | $ (19,387)
Deemed dividend on convertible exchangeable preferred shares |  |
Dividend on convertible exchangeable preferred shares | $ (201) | $ (200)
Net loss applicable to common shareholders | $ (14,543) | $ (19,587)
Basic and diluted earnings per common share: |  |
Net loss per share, continuing operations - basic and diluted (in dollars per share) | $ (0.45) | $ (0.89)
Net income per share, discontinued operations - basic and diluted (in dollars per share) | 0.00 | 0.00
Net loss per share - basic and diluted (in dollars per share) | $ (0.45) | $ (0.89)
Weighted average common shares outstanding (in shares) | 32,557,146 | 21,955,381

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- References No definition available. + Details
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- Definition The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.4) -URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 330 -SubTopic 10 -Section 30 -Paragraph 8 -URI http://asc.fasb.org/extlink&oid=51677171&loc=d3e3636-108311 + Details
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- Definition Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS). + References No definition available. + Details
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