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Accrued and Other Current Liabilities (Tables)
 12 Months Ended
Dec. 31, 2015
Accrued and Other Current Liabilities  
Schedule of accrued and other current liabilities
​ ​ ​
December 31,
 ​
​ ​ ​
2014
 ​ ​
2015
 ​
Accrued research and development
 ​ ​ ​ $ 4,161 ​ ​ ​ ​ $ 3,284 ​ ​
Accrued legal and professional fees
 ​ ​ ​ ​ 303 ​ ​ ​ ​ ​ 291 ​ ​
Other current liabilities
 ​ ​ ​ ​ 162 ​ ​ ​ ​ ​ 163 ​ ​
​ ​ ​ ​ $ 4,626 ​ ​ ​ ​ $ 3,738