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Taxes (Tables)
 12 Months Ended
Dec. 31, 2015
Taxes  
Schedule of components of (loss) gain before taxes from continuing operations
​ ​ ​
Year Ended 
December 31, 
2014
 ​ ​
Year Ended 
December 31, 
2015
 ​
Domestic
 ​ ​ ​ $ (2,898) ​ ​ ​ ​ $ (2,520) ​ ​
Foreign
 ​ ​ ​ ​ (19,751) ​ ​ ​ ​ ​ (13,966) ​ ​
Loss from continuing operations before taxes
 ​ ​ ​ $ (22,649) ​ ​ ​ ​ $ (16,486) ​ ​
​
 
Schedule of benefit for income taxes from continuing operations
​ ​ ​
Year Ended 
December 31, 
2014
 ​ ​
Year Ended 
December 31, 
2015
 ​
Current – domestic
 ​ ​ ​ $ 34 ​ ​ ​ ​ $ — ​ ​
Current – foreign
 ​ ​ ​ ​ 3,209 ​ ​ ​ ​ ​ 2,144 ​ ​
Current – total
 ​ ​ ​ ​ 3,243 ​ ​ ​ ​ ​ 2,144 ​ ​
Deferred – domestic
 ​ ​ ​ ​ — ​ ​ ​ ​ ​ — ​ ​
Income tax benefit
 ​ ​ ​ $ 3,243 ​ ​ ​ ​ $ 2,144 ​ ​
​
Schedule of reconciliation of the (benefit) provision for income taxes from continuing operations with the amount computed by applying the statutory federal tax rate to loss before income taxes
​ ​ ​
Year Ended 
December 31, 
2014
 ​ ​
Year Ended 
December 31, 
2015
 ​
Loss from continuing operations before taxes
 ​ ​ ​ $ (22,649) ​ ​ ​ ​ $ (16,486) ​ ​
Income tax expense computed at statutory federal tax rate
 ​ ​ ​ ​ (7,701) ​ ​ ​ ​ ​ (5,605) ​ ​
Disallowed expenses and non-taxable income
 ​ ​ ​ ​ 406 ​ ​ ​ ​ ​ 27 ​ ​
Loss surrendered to generate R&D credit
 ​ ​ ​ ​ 7,294 ​ ​ ​ ​ ​ 2,479 ​ ​
Additional research and development tax relief
 ​ ​ ​ ​ (7,262) ​ ​ ​ ​ ​ (3,402) ​ ​
Change in valuation allowance
 ​ ​ ​ ​ (4,963) ​ ​ ​ ​ ​ (4,189) ​ ​
Research and development credit – prior years
 ​ ​ ​ ​ — ​ ​ ​ ​ ​ — ​ ​
Foreign items, including change in tax rates, and other
 ​ ​ ​ ​ 3,555 ​ ​ ​ ​ ​ 6,882 ​ ​
Other foreign items
 ​ ​ ​ ​ 5,428 ​ ​ ​ ​ ​ 1,664 ​ ​
​ ​ ​ ​ $ (3,243) ​ ​ ​ ​ $ (2,144) ​ ​
​
Schedule of significant components of the entity's deferred tax assets
​ ​ ​
December 31,
 ​
​ ​ ​
2014
 ​ ​
2015
 ​
Net operating loss carryforwards
 ​ ​ ​ $ 45,060 ​ ​ ​ ​ $ 41,003 ​ ​
Depreciation, amortization and impairment of property and equipment
 ​ ​ ​ ​ 81 ​ ​ ​ ​ ​ 101 ​ ​
Stock options
 ​ ​ ​ ​ 1,815 ​ ​ ​ ​ ​ 2,193 ​ ​
Accrued expenses
 ​ ​ ​ ​ 179 ​ ​ ​ ​ ​ — ​ ​
Research and development credits
 ​ ​ ​ ​ 4,332 ​ ​ ​ ​ ​ 4,021 ​ ​
Other
 ​ ​ ​ ​ 78 ​ ​ ​ ​ ​ 38 ​ ​
Translation adjustment
 ​ ​ ​ ​ — ​ ​ ​ ​ ​ — ​ ​
Deferred tax assets
 ​ ​ ​ ​ 51,545 ​ ​ ​ ​ ​ 47,356 ​ ​
Valuation allowance for deferred tax assets
 ​ ​ ​ ​ (51,545) ​ ​ ​ ​ ​ (47,356) ​ ​
Net deferred taxes
 ​ ​ ​ $ — ​ ​ ​ ​ $ — ​ ​
​