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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Revenues:    
Grant revenue $ 1,694 $ 1,734
Collaboration and research and development revenue 250  
Total revenues 1,944 1,734
Operating expenses:    
Research and development 12,382 18,277
General and administrative 5,732 5,894
Total operating expenses 18,114 24,171
Operating loss (16,170) (22,437)
Other income (expense):    
Change in valuation of financial instruments associated with stock purchase agreement (51) (342)
Change in valuation of liabilities measured at fair value   20
Foreign exchange gains (368) (10)
Interest income 9 6
Other income, net 94 114
Total other income (expense), net (316) (212)
Loss from continuing operations before taxes (16,486) (22,649)
Income tax benefit 2,144 3,243
Net loss from continuing operations (14,342) (19,406)
Discontinued operations:    
Income from discontinued operations   29
Income tax on discontinued operations   (10)
Net income from discontinued operations   19
Net loss $ (14,342) $ (19,387)
Deemed dividend on convertible exchangeable preferred shares
Dividend on convertible exchangeable preferred shares $ (201) $ (200)
Net loss applicable to common shareholders $ (14,543) $ (19,587)
Basic and diluted earnings per common share:    
Net loss per share, continuing operations - basic and diluted (in dollars per share) $ (0.45) $ (0.89)
Net income per share, discontinued operations - basic and diluted (in dollars per share) 0.00 0.00
Net loss per share - basic and diluted (in dollars per share) $ (0.45) $ (0.89)
Weighted average common shares outstanding (in shares) 32,557,146 21,955,381