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Stock-Based Compensation Arrangements (Details 1) - Stock options - USD ($)
$ / shares in Units, $ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Number of Options Outstanding    
Options outstanding at the beginning of the period (in shares) 1,010,298 949,685
Granted (in shares) 1,470,281 63,000
Exercised (in shares)
Cancelled / forfeited (in shares) (5,000) (2,387)
Options outstanding at the end of the period (in shares) 2,475,579 1,010,298
Unvested at December 31, 2015 1,577,211  
Vested and exercisable at December 31, 2015 898,368  
Weighted Average Exercise Price Per Share    
Options outstanding at the beginning of the period (in dollars per share) $ 14.24 $ 15.02
Granted (in dollars per share) 0.63 3.11
Cancelled / forfeited (in dollars per share) 67.82 31.08
Options outstanding at the end of the period (in dollars per share) 6.05 $ 14.24
Unvested at the end of the period (in dollars per share) 1.01  
Vested and exercisable at the end of the period (in dollars per share) $ 14.91  
Weighted Average Remaining Contractual Term (Years)    
Options outstanding 8 years 1 month 2 days 7 years 4 months 17 days
Unvested at the end of the period 9 years 7 months 10 days  
Vested and exercisable at the end of the period 5 years 5 months 1 day 6 years 6 months 29 days
Aggregate Intrinsic Value    
Options outstanding $ 152
Unvested at the end of the period  
Vested and exercisable at the end of the period