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Organization of the Company and Basis of Presentation (Details Textuals) - USD ($)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
May 27, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Organization Of Company And Basis Of Presentation Line Items        
Net loss   $ (11,791) $ (14,342)  
Accumulated deficit   (335,039) (323,159)  
Cash and cash equivalents   $ 16,520 $ 20,440 $ 24,189
Stockholders' equity, Reverse stock split one-for-twelve      
Common stock, par value (in dollars per share)   $ 0.001 $ 0.001  
Common stock, shares outstanding (in shares)   4,256,829 2,965,208  
Before Reverse Stock Split        
Organization Of Company And Basis Of Presentation Line Items        
Common stock, shares outstanding (in shares) 36,075,730      
After Reverse Stock Split        
Organization Of Company And Basis Of Presentation Line Items        
Common stock, shares outstanding (in shares) 3,006,311