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CONSOLIDATED STATEMENTS OF OPERATIONS (LOSS) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Revenues:    
Grant revenue $ 843 $ 1,694
Collaboration and research and development revenue   250
Total revenues 843 1,944
Operating expenses:    
Research and development 9,477 12,382
General and administrative 5,516 5,732
Total operating expenses 14,993 18,114
Operating loss (14,150) (16,170)
Other income (expense):    
Change in valuation of financial instruments associated with stock purchase agreement   (51)
Foreign exchange gains (losses) 273 (368)
Interest income 37 9
Other income, net 66 94
Total other income (expense), net 376 (316)
Loss from continuing operations before taxes (13,774) (16,486)
Income tax benefit 1,983 2,144
Net loss (11,791) (14,342)
Dividend on convertible exchangeable preferred shares (200) (201)
Net loss applicable to common shareholders $ (11,991) $ (14,543)
Basic and diluted earnings per common share:    
Net loss per share - basic and diluted (in dollars per share) $ (3.50) $ (5.36)
Weighted average common shares outstanding (in shares) 3,424,976 2,713,096