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Taxes (Details 3) - USD ($) $ in Thousands | Dec. 31, 2017 | Dec. 31, 2016
--- | --- | ---
Net operating loss and tax credit carryforwards |  |
Net operating loss and tax credit carryforwards | $ 38,948 | $ 42,851
Depreciation, amortization and impairment of property and equipment | 111 | 137
Stock options | 1,807 | 2,365
Research and development credits | 4,021 | 4,021
Other | 0 | 0
Deferred tax assets | 44,887 | 49,374
Valuation allowance for deferred tax assets | (44,887) | (49,374)
Net deferred tax assets | $ 0 | $ 0

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