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Taxes (Details 3) - USD ($)
$ in Thousands
Dec. 31, 2017
Dec. 31, 2016
Net operating loss and tax credit carryforwards    
Net operating loss and tax credit carryforwards $ 38,948 $ 42,851
Depreciation, amortization and impairment of property and equipment 111 137
Stock options 1,807 2,365
Research and development credits 4,021 4,021
Other 0 0
Deferred tax assets 44,887 49,374
Valuation allowance for deferred tax assets (44,887) (49,374)
Net deferred tax assets $ 0 $ 0