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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Cash flows from operating activities:    
Net loss $ (7,470) $ (11,791)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation expense 32 133
Gain on disposal of property and equipment   (12)
Stock-based compensation expense 266 782
Changes in operating assets and liabilities:    
Prepaid expenses and other assets 1,232 439
Accounts payable and other current liabilities (1,540) 370
Net cash used in operating activities (7,480) (10,079)
Cash flows from investing activities:    
Purchases of property and equipment (13) (3)
Proceeds from sale of property and equipment   12
Net cash provided by (used in) investing activities (13) 9
Cash flows from financing activities:    
Proceeds from issuance of equity securities, net of issuance costs 14,749 6,794
Proceeds from the exercise of stock options and warrants, net of issuance costs 200  
Payment of preferred stock dividend (201) (200)
Net cash provided by financing activities 14,748 6,594
Effect of exchange rate changes on cash and cash equivalents 135 (444)
Net decrease in cash and cash equivalents 7,390 (3,920)
Cash and cash equivalents at beginning of period 16,520 20,440
Cash and cash equivalents at end of period 23,910 16,520
Cash received during the period for:    
Interest 118 38
Taxes 1,815 1,965
Non cash financing activities:    
Accrual of preferred stock dividends $ 50 $ 50