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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019
Operating activities: |  |
Net loss | $ (8,445) | $ (7,830)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 20 | 20
Gain on disposal of property and equipment |  | (38)
Stock-based compensation | 430 | 466
Changes in lease liability | (93) | (71)
Changes in operating assets and liabilities: |  |
Prepaid expenses and other assets | 124 | 214
Accounts payable and other current liabilities | 30 | (2,208)
Net cash used in operating activities | (7,934) | (9,447)
Investing activities: |  |
Purchase of property, plant and equipment | (96) | (10)
Proceeds from sale of property and equipment |  | 38
Net cash provided by (used in) investing activities | (96) | 28
Financing activities: |  |
Proceeds from issuing common stock, preferred stock and pre-funded warrants, net of issuance costs | 29,705 | 4,049
Payment of preferred stock dividend | (201) | (201)
Net cash provided by financing activities | 29,504 | 3,848
Effect of exchange rate changes on cash and cash equivalents | 47 | (48)
Net increase in cash and cash equivalents | 21,521 | (5,619)
Cash and cash equivalents, beginning of period | 11,885 | 17,504
Cash and cash equivalents, end of period | 33,406 | 11,885
Supplemental cash flow information: |  |
Cash received during the period for: Interest | 42 | 224
Cash received during the period for: Taxes | 1,291 | 1,163
Lease liability |  | (1,505)
Right-of-use asset |  | 1,385
Non cash financing activities: |  |
Accrual of preferred stock dividends | $ 50 | $ 50

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