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Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2020

Stock-Based Compensation [Abstract]

Schedule of Stock Based Compensation Expense

Stock based compensation has been reported within expense line items on the consolidated statement of operations for the years ended 2019 and 2020 as shown in the following table (in thousands):

		Year Ended
		December 31,
		2019			2020
Research and development			166		$	152
General and administrative			300			278
Stock-based compensation costs before income taxes		$	466		$	430

Schedule of Share Option Activity

A summary of the share option activity and related information is as follows:

							Weighted
				Weighted			Average
		Number of		Average			Remaining		Aggregate
		Options		Exercise			Contractual		Intrinsic
		Outstanding		Price Per Share			Term (Years)		Value ($000)
Options outstanding at December 31, 2018		41,581		$	133.60		8.13		$	—
Granted		77,514		$	14.20		—			—
Exercised		—			—		—			—
Cancelled/forfeited		(18,816)		$	64.60		—			—
Options outstanding at December 31, 2019		100,279		$	54.40		8.62		$	4
Granted		511,800		$	4.17		—			—
Exercised		—			—		—			—
Cancelled/forfeited		(9,396)		$	101.05		—			—
Options outstanding at December 31, 2020		602,683		$	11.01		9.39		$	1,861
Unvested at December 31, 2020		525,010		$	4.64		9.80		$	1,829
Vested and exercisable at December 31, 2020		77,673		$	54.05		6.61		$	32

Schedule of Fair Value of the Stock Options Granted

The fair value of the stock options granted is calculated using the Black-Scholes option-pricing model as prescribed by ASC 718 using the following assumptions:

		Year Ended		Year Ended
		December 31, 2019		December 31, 2020
Expected term (years)		5 – 6		5 – 6
Risk free interest rate		2.105 – 2.610%		0.410% – 0.570%
Volatility		103 – 110%		96 – 115%
Expected dividend yield over expected term		0.00%		0.00%
Resulting weighted average grant date fair value		$14.20		$3.47

Schedule of Restricted Stock Units Activity

Summarized information for restricted stock units’ activity for the year ended December 31, 2020 is as follows:

				Weighted
		Number of		Average
		Options		Grant Date
		Outstanding		Value Per Share
Restricted Stock Units outstanding at December 31, 2019		14,000		$	10.60
Granted		3,938		$	15.20
Cancelled/forfeited		(1,414)		$
Restricted Stock Units outstanding at December 31, 2020		16,524		$	11.30
Unvested at December 31, 2020		16,524		$	11.30
Vested and exercisable at December 31, 2020		—		$	—

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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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