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Stockholders Equity (Narrative) (Details) - USD ($)
 1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Oct. 01, 2021
Aug. 12, 2021
Mar. 12, 2021
Dec. 22, 2020
Dec. 18, 2020
Apr. 24, 2020
Apr. 21, 2020
Jul. 31, 2017
Sep. 30, 2021
Mar. 31, 2021
Sep. 30, 2021
Dec. 31, 2020
Dec. 31, 2017
Apr. 14, 2020
Class of Stock [Line Items]                            
Aggregate offering price                 $ 2,955,000 $ 13,501,000        
Common stock, par value (in dollars per share)                 $ 0.001   $ 0.001 $ 0.001   $ 0.001
Preferred stock, par value (in dollars per share)                 $ 0.001   $ 0.001 $ 0.001    
Number of share sold under the sales agreement                 563,625   563,625      
Proceeds from issuance of common stock, net of issuance costs                 $ 3,000,000.0   $ 3,000,000.0      
Common stock, shares outstanding (in shares)                 9,797,735   9,797,735 6,246,896    
Subsequent Events [Member]                            
Class of Stock [Line Items]                            
Number of share sold under the sales agreement 170,800                          
Proceeds from issuance of common stock, net of issuance costs $ 900,000                          
July 2017 - Underwritten Public Offering [Member]                            
Class of Stock [Line Items]                            
Warrants, exercise price per share                 $ 40.00   $ 40.00      
Percentage of outstanding common stock                     4.99%      
Outstanding common stock at election of purchaser                     9.99%      
Warrants outstanding                 374,525   374,525      
Warrants exercised                 0   0      
March 2021 Equity Financing [Member]                            
Class of Stock [Line Items]                            
Proceeds from issuance of common stock, net of issuance costs     $ 13,500,000                      
Common Stock [Member]                            
Class of Stock [Line Items]                            
Aggregate offering price                 $ 1,000 $ 2,000        
Number of shares issued (in shares)                 563,625 2,078,214        
Cantor Fitzgerald & Co. [Member] | At Market Issuance [Member]                            
Class of Stock [Line Items]                            
Selling commissions, percentage   3.00%                        
Cantor Fitzgerald & Co. [Member] | Maximum [Member] | At Market Issuance [Member]                            
Class of Stock [Line Items]                            
Aggregate offering price   $ 50,000,000.0                        
Acorn Bioventures, LP [Member]                            
Class of Stock [Line Items]                            
Warrants to purchase shares                 669,854   669,854      
Number of share sold under the sales agreement         485,912                  
Warrant outstanding Term                 5 years   5 years      
Warrants, exercise price per share                 $ 4.13   $ 4.13      
Warrants exercised                 0   0      
Co-Placement Agents [Member]                            
Class of Stock [Line Items]                            
Sell of stock, price per share             $ 5.00              
Proceeds from issuance of stocks/warrants           $ 18,300,000                
Warrants, exercise price per share                 $ 5.00   $ 5.00      
Number of warrant to purchase each share of our common stock                 1   1      
Warrants outstanding                 2,190,000   2,190,000      
Warrants exercised                     909,000      
Co-Placement Agents [Member] | Pre Funded Warrants [Member]                            
Class of Stock [Line Items]                            
Number of share sold under the sales agreement             2,090,000              
Sell of stock, price per share             $ 4.999              
Warrants, exercise price per share             $ 0.001              
Number of warrant to purchase each share of our common stock             1              
Percentage of outstanding common stock             4.99%              
Outstanding common stock at election of purchaser             9.99%              
Shares issued on conversion of prefunded warrants           2,090,000                
Co-Placement Agents [Member] | Common Stock Warrants [Member]                            
Class of Stock [Line Items]                            
Warrants to purchase shares             4,000,000              
Warrant outstanding Term             5 years              
Warrants, exercise price per share             $ 5.00              
Number of warrant to purchase each share of our common stock             1              
Percentage of outstanding common stock                     4.99%      
Outstanding common stock at election of purchaser                     9.99%      
Notice period from the holder to increase the percentage of ownership of outstanding common stock after exercise of warrants                     61 days      
Fractional shares issued                     0      
Oppenheimer & Co. Inc. [Member] | March 2021 Equity Financing [Member]                            
Class of Stock [Line Items]                            
Number of share sold under the sales agreement     1,807,143                      
Sale of stock, number of additional shares issued in transaction     271,071                      
Share issue price per share     $ 7.00                      
Common Stock [Member] | Co-Placement Agents [Member]                            
Class of Stock [Line Items]                            
Number of share sold under the sales agreement             1,910,000              
6% Convertible Exchangeable Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Preferred stock, shares issued                 335,273   335,273 335,273    
Preferred stock, shares outstanding                 335,273   335,273 335,273    
Share issue price per share                 $ 10.00   $ 10.00      
Dividend rate on convertible exchangeable preferred stock (in percent)                     6.00% 6.00%    
Liquidation preference (in dollars per share)                 $ 10.00   $ 10.00      
Convertible preferred stock, terms of conversion                     The Company may automatically convert the 6% Preferred Stock into common stock if the per share closing price of the Company’s common stock has exceeded $59,220, which is 150% of the conversion price of the 6% Preferred Stock, for at least 20 trading days during any 30 day trading period, ending within five trading days prior to notice of automatic conversion.      
Interest rate of Convertible Subordinated Debentures (as a percent)                 6.00%   6.00%      
Accrued and unpaid dividends                 $ 50,291   $ 50,291      
Redemption price per share (in dollars per share)                 $ 10.00   $ 10.00      
Debt principal amount per share, basis for exchange (in dollars per share)                     $ 10.00      
Debt instrument, term                     25 years      
Series A Convertible Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Preferred stock, par value (in dollars per share)                 $ 0.001   $ 0.001 $ 0.001    
Preferred stock, shares issued               8,872 264   264 264    
Preferred stock, shares outstanding                 264   264 264    
Number of common shares issued upon conversion               215,200            
Number of shares converted                     6,600   8,608  
Price per share used to determine number of shares of common stock               $ 1,000            
Conversion price of convertible preferred stock               $ 40.00            
Conversion percentage               9.99%            
Measurement period of consecutive trading days used in determining whether specified triggers are met which would allow the entity to require the conversion of all or part of outstanding preferred stock                     30 days      
Percentage of blocker provision               4.99%            
Series A Convertible Preferred Stock [Member] | Minimum [Member]                            
Class of Stock [Line Items]                            
Percentage by which the weighted average price of common stock during the measurement period exceeds the initial conversion price which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted                     300.00%      
Threshold amount of daily trading volume on each trading day during the measurement period which triggers the right of the entity to cause all or part of the outstanding preferred stock to be converted                     $ 500,000      
Series B Convertible Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Preferred stock, par value (in dollars per share)                 $ 0.001   $ 0.001 $ 0.001    
Preferred stock, shares issued                 237,745   237,745 237,745    
Preferred stock, shares outstanding                 237,745   237,745 237,745    
Sell of stock, price per share                 $ 4.18   $ 4.18      
Effective Conversion price per share                     $ 3.18      
Number of common shares issued upon conversion                 5   5      
Series B Convertible Preferred Stock [Member] | Acorn Bioventures, LP [Member]                            
Class of Stock [Line Items]                            
Warrants to purchase shares         669,854                  
Number of share sold under the sales agreement         237,745                  
Sell of stock, price per share         $ 4.18                  
Warrants exercisable date         Dec. 18, 2020                  
Warrant outstanding Term         5 years                  
Proceeds from issuance of stocks/warrants       $ 6,900,000                    
Warrants, exercise price per share         $ 4.13                  
Number of warrant to purchase each share of our common stock         1                  
Warrants outstanding         400,000