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Significant Contracts (Narrative) (Details) $ in Millions |  | 12 Months Ended
--- | --- | ---
Oct. 01, 2018 item | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($)
Clinical Collaboration Agreement [Member] | The University of Texas MD Anderson Cancer Center [Member] |  |  |
Supply Commitment [Line Items] |  |  |
Term of agreement | 3 years |  |
Number of clinical studies conducted | item | 4 |  |
Daiichi Sankyo |  |  |
Supply Commitment [Line Items] |  |  |
Future milestone payments payable |  | $ 10.0 |
Period for which royalties will be paid following first commercial sale of licensed products |  | 10 years |
Notice period for termination of license by the entity for technical, scientific, efficacy, safety, or commercial reasons |  | 6 months |
Notice period for termination of license after launch of a sapacitabine-based product by the entity, or by either party for material default |  | 12 months |
Notice period for right of first refusal if third party to be appointed to develop or commercialize a sapacitabine-based product in Japan |  | 60 days |
Milestones earned |  | $ 0.0 | $ 0.0

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- Definition The required notification period for right of first refusal if entity elects to appoint a third party to develop or commercialize a sapacitabine-based product in Japan. + References No definition available. + Details
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- Definition Represents the notice period for the termination of license after a launch of a sapacitabine-based product, or by either party for material default. + References No definition available. + Details
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- Definition Represents the period for which royalties will be paid following the first commercial sale of licensed products in the country. + References No definition available. + Details
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- Definition Represents the notice period for the termination of license by the reporting entity for technical, scientific, efficacy, safety, or commercial reasons. + References No definition available. + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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