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Stock-Based Compensation (Tables)

12 Months Ended

Dec. 31, 2021

Stock-Based Compensation [Abstract]

Schedule of Stock Based Compensation Expense

Stock based compensation has been reported within expense line items on the consolidated statement of operations for the years ended 2020 and 2021 as shown in the following table (in thousands):

​	​	​	​	​	​	​
​		Year Ended
​		December 31,
​	​	2020			2021
General and administrative	​		278	​	$	819
Research and development	​	​	152	​	​	338
Stock-based compensation costs before income taxes	​	$	430	​	$	1,157

Schedule of Share Option Activity

A summary of the share option activity and related information is as follows:

​	​	​	​	​	​	​	​	​	​	​
​		​		​	​		Weighted		​	​
​		​		Weighted			Average		​	​
​		Number of		Average			Remaining		Aggregate
​	​	Options		Exercise			Contractual	​	Intrinsic
​	​	Outstanding	​	Price Per Share			Term (Years)	​	Value ($000)
Options outstanding at December 31, 2019		100,279	​	$	54.40		8.62	​	$	4
Granted		511,800	​	$	4.17		—	​		—
Exercised		—	​	​	—		—	​		—
Cancelled/forfeited		(9,396)	​	$	101.05		—	​		—
Options outstanding at December 31, 2020		602,683	​	$	11.01		9.39	​	$	4
Granted		552,153	​	$	4.26		—	​		—
Exercised		(6,600)	​	​	3.35		—	​		—
Cancelled/forfeited		(48,879)	​	$	14.18		—	​		—
Options outstanding at December 31, 2021		1,099,357	​	$	7.53		8.99	​	$	189
​	​	​	​	​	​	​	​	​	​	​
Unvested at December 31, 2021		801,924	​	$	4.14		9.49	​	$	180
Vested and exercisable at December 31, 2021		297,433	​	$	16.66		7.62	​	$	9

Schedule of Fair Value of the Stock Options Granted

The fair value of the stock options granted is calculated using the Black-Scholes option-pricing model as prescribed by ASC 718 using the following assumptions:

​	​	​	​	​
​	​	​	​	​
​	​	Year ended	​	Year ended
​		December 31, 2020		December 31, 2021
Expected term (years)		5 – 6		5 – 6
Risk free interest rate		0.410% – 0.570%	​	0.420% – 1.290%
Volatility		96 – 115%	​	95 – 102%
Expected dividend yield over expected term		0.00%	​	0.00%
Resulting weighted average grant date fair value		$3.47	​	$3.36

Schedule of Restricted Stock Units Activity

​

​	​	​	​	​	​
​		​		Weighted
​		​		Average
​	​	Restricted		Grant Date
​	​	Stock Units	​	Value Per Share
Restricted Stock Units outstanding at December 31, 2020		16,524	​	$	11.30
Granted	​	18,992	​	​	6.69
Cancelled/forfeited	​	(16,524)	​	​	15.20
Restricted Stock Units outstanding at December 31, 2021	​	18,992	​	$	6.69
​	​	​	​	​	​
Unvested at December 31, 2021		18,992	​	$	6.69
Vested and exercisable at December 31, 2021		—	​	$	—

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Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement.

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Tabular disclosure of the number and weighted-average grant date fair value for restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock units that were granted, vested, or forfeited during the year.

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Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value.

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Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions.

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