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v3.22.1

Stock Based Compensation - Narrative (Details) - $ / shares |  | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Apr. 25, 2022 | Mar. 31, 2022 | Mar. 31, 2021 | Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019 | Oct. 31, 2020
Stock-based compensation |  |  |  |  |  |  |
Common stock, shares issued |  | 9,993,135 |  | 9,993,135 |  |  |
Options granted (in shares) |  | 265,000 | 73,669 |  |  |  |
Options exercised (in shares) |  | 0 | 0 |  |  |  |
Minimum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  | 1 year |  |  |  |  |
Options granted, grant date fair value |  | $ 2.62 | $ 5.40 |  |  |  |
Maximum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  | 4 years |  |  |  |  |
Options granted, grant date fair value |  | $ 2.90 | $ 6.14 |  |  |  |
Stock options |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Options granted (in shares) |  | 265,000 |  |  |  |  |
Options exercised (in shares) |  | 0 |  |  |  |  |
Restricted Stock Units (RSUs) [Member] |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Restricted Stock Units, Granted |  | 0 |  | 18,992 | 3,938 | 14,000 |
Stock units forfeited |  |  |  |  | 1,491 |  |
Restricted Stock Units outstanding/unvested |  | 18,992 |  | 18,992 |  |  |
Restricted stock units, grant date fair value |  | $ 6.69 |  | $ 6.69 |  |  |
Restricted Stock Units (RSUs) [Member] | Fulfillment of Certain Clinical Conditions [Member] |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Restricted Stock Units outstanding/unvested |  |  |  |  | 16,524 |  |
Restricted Stock Units (RSUs) [Member] | Minimum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  |  |  | 1 year |  |  |
Restricted Stock Units (RSUs) [Member] | Maximum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  |  |  | 3 years |  |  |
2018 Equity Incentive Plan (the "2018 Plan") [Member] |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Number of shares reserved for issuance |  | 260,794 |  |  |  |  |
Life of stock option awards granted |  | 10 years |  |  |  |  |
Number of authorized additional shares to be issued | 500,000 |  |  |  |  |  |
2018 Equity Incentive Plan (the "2018 Plan") [Member] | Minimum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  | 1 year |  |  |  |  |
2018 Equity Incentive Plan (the "2018 Plan") [Member] | Maximum |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Stock awards vesting period |  | 4 years |  |  |  |  |
Inducement Equity Incentive Plan 2020 [Member] |  |  |  |  |  |  |
Stock-based compensation |  |  |  |  |  |  |
Number of shares reserved for issuance |  | 80,000 |  |  |  |  |
Number of authorized shares |  |  |  |  |  |  | 200,000
Common stock, shares issued |  | 120,000 |  |  |  |  |

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- Definition The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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